bioskills-context-specific-models

name	bioskills-context-specific-models
description	Build a tissue/condition-specific metabolic model by constraining a generic genome-scale model with transcriptomics data using GIMME, iMAT, or GTEx-based tissue extraction, then validate against the original model.
domain	single-cell
primary_tool	COBRApy
methods	["cobra","GIMME","iMAT","numpy","pandas"]
macro_tags	["context-specific-model","metabolic-modeling","transcriptomics-integration","GIMME","iMAT","tissue-specific"]
micro_tags	["cobra","GIMME","iMAT","numpy","pandas","gpr-mapping","normalization","biomass-constraint","milp","gtex","fba","validation"]
source	bioskills-context-specific-models
status	active
enabled	true

Bioskills Context Specific Models