القائمة
Multiple sequence alignment and conservation analysis using MUSCLE
التثبيت باستخدام Codex أو Claude انسخ هذا Prompt والصقه في Codex أو Claude أو مساعد آخر ليراجع صفحة Skill ويثبّتها لك.
استنادا إلى تصنيف SOC المهني
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| name | evolutionary-conservation |
| description | Multiple sequence alignment and conservation analysis using MUSCLE |
| metadata | {"openclaw":{"requires":{"env":["OPENAI_API_KEY"],"bins":["python3"],"anyBins":["muscle","muscle5"]},"primaryEnv":"OPENAI_API_KEY"}} |
Analyze evolutionary conservation of protein sequences using multiple sequence alignment.
Requires: MUSCLE v5 binary (muscle or muscle5) on PATH.
# From a FASTA file of homologous sequences
python skills/evolutionary-conservation/scripts/run_conservation.py \
--input-fasta sequences.fasta --output-dir results/
# From bare sequences
python skills/evolutionary-conservation/scripts/run_conservation.py \
--sequences MTEYKLVV... MTEYKLVVV... --output-dir results/
# With artifact DAG tracking
python skills/evolutionary-conservation/scripts/run_conservation.py \
--input-fasta sequences.fasta --output-dir results/ \
--artifact-store ./artifact_store
--input-fasta: Path to unaligned FASTA file (mutually exclusive with --sequences)--sequences: Bare protein sequences to align (space-separated)--output-dir: Directory for output files (default: conservation_output)--method: Scoring method — shannon or property (default: shannon)--conserved-threshold: Score threshold for conserved regions (default: 0.8)--min-region-length: Minimum contiguous length for a conserved region (default: 3)--muscle-bin: Explicit path to MUSCLE binary (auto-detected if omitted)--artifact-store: Root directory for artifact DAG storage (optional)