القائمة
Assess alignment quality with coverage depth, mapping rates, insert size, and on-target metrics using samtools, mosdepth, and picard.
التثبيت باستخدام Codex أو Claude انسخ هذا Prompt والصقه في Codex أو Claude أو مساعد آخر ليراجع صفحة Skill ويثبّتها لك.
استنادا إلى تصنيف SOC المهني
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| name | genome-alignment-qc |
| description | Assess alignment quality with coverage depth, mapping rates, insert size, and on-target metrics using samtools, mosdepth, and picard. |
.bam + .bai).samtools stats and samtools flagstat for mapping summary.samtools idxstats for per-chromosome read counts.mosdepth for coverage distribution (genome-wide, or restricted to target BED).picard CollectInsertSizeMetrics for insert size distribution.picard CollectAlignmentSummaryMetrics for detailed alignment statistics.knowledge/sources/genomics/quality-thresholds.md).samtools stats and samtools flagstat output files.mosdepth coverage files (.mosdepth.global.dist.txt, .per-base.bed.gz if enabled).$PATH..bai) missing or out of date relative to the BAM file.chr1 vs 1)..dict).