renal-metabolic

name	renal-metabolic
description	Use when calculating renal function estimates, electrolyte corrections, acid-base physiology metrics, lipid estimates, or BMI. Includes CKD-EPI 2021, Cockcroft-Gault, anion gap, Winters formula, A-a gradient, Friedewald LDL, and related tools.

Renal and Metabolic Calculators

Description

This skill provides structured calculation guidance for common renal and metabolic formulas used in clinical practice. It supports accurate input collection, calculation, interpretation, and safety caveats.

Quick Reference

Tool	Use
CKD-EPI 2021 (Creatinine)	Estimate eGFR without race variable
CKD-EPI 2021 (Cystatin C)	eGFR using cystatin C or combined equation
Cockcroft-Gault (CrCl)	Drug dosing using creatinine clearance
Corrected Calcium	Adjust calcium for albumin
Corrected Sodium	Adjust sodium in hyperglycemia
Anion Gap	Metabolic acidosis assessment
Winters Formula	Expected pCO2 in metabolic acidosis
A-a Gradient	Oxygenation and V/Q evaluation
Friedewald LDL	Estimate LDL-C from standard lipids
BMI	Body mass index classification

Interactive Mode (Lightweight)

1. Confirm the clinical context and intended tool.
2. Collect required inputs with units and timing.
3. Validate inputs and resolve missing data.
4. Calculate and present results with interpretation.
5. Provide safety caveats and limitations.

Calculators

• CKD-EPI 2021 (Creatinine)
• CKD-EPI 2021 (Cystatin C)
• Cockcroft-Gault (CrCl)
• Corrected Calcium
• Corrected Sodium
• Anion Gap
• Winters Formula
• A-a Gradient
• Friedewald LDL
• BMI

Safety and Limitations

• Support tool only; not diagnostic or prescriptive.
• Use local policies and clinical judgment.
• Many formulas have population limits and invalid ranges.

References

See: references/renal-metabolic-sources.md