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bioskills-crispr-screen-pipeline

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UpdatedJuly 6, 2026 at 12:06

End-to-end pooled and single-cell CRISPR screen pipeline: library validation, guide counting, six-stage QC, copy-number/batch correction, design-matched hit calling, and tier-based consensus.

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ai4nucleome

ai4nucleome/BioMaster

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SKILL.md

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name	bioskills-crispr-screen-pipeline
description	End-to-end pooled and single-cell CRISPR screen pipeline: library validation, guide counting, six-stage QC, copy-number/batch correction, design-matched hit calling, and tier-based consensus.
domain	single-cell
primary_tool	MAGeCK
methods	["MAGeCK","BAGEL2","drugZ","JACKS","Chronos","CRISPRcleanR","MAGeCKFlute","pertpy"]
macro_tags	["crispr-screen","pooled-screen","hit-calling","quality-control","consensus","workflow"]
micro_tags	["mageck","bagel2","drugz","jacks","chronos","crisprcleanr","mageckflute","gini","pr-auc","copy-number","batch-correction","volcano"]
source	bioskills-crispr-screen-pipeline
status	active
enabled	true

Bioskills Crispr Screen Pipeline

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name	bioskills-crispr-screen-pipeline
description	End-to-end pooled and single-cell CRISPR screen pipeline: library validation, guide counting, six-stage QC, copy-number/batch correction, design-matched hit calling, and tier-based consensus.
domain	single-cell
primary_tool	MAGeCK
methods	["MAGeCK","BAGEL2","drugZ","JACKS","Chronos","CRISPRcleanR","MAGeCKFlute","pertpy"]
macro_tags	["crispr-screen","pooled-screen","hit-calling","quality-control","consensus","workflow"]
micro_tags	["mageck","bagel2","drugz","jacks","chronos","crisprcleanr","mageckflute","gini","pr-auc","copy-number","batch-correction","volcano"]
source	bioskills-crispr-screen-pipeline
status	active
enabled	true