risk-of-bias

Assess risk of bias in research studies for systematic reviews. Use when: (1) Conducting systematic reviews, (2) Evaluating study quality, (3) GRADE assessments, (4) Meta-analysis planning.

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Repository: ForceInjection/domain-driven-design-skills
Last source activity: May 8, 2026 at 03:07
Detected SKILL.md language: English
Stars: 25
Forks: 7

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name	risk-of-bias
description	Assess risk of bias in research studies for systematic reviews. Use when: (1) Conducting systematic reviews, (2) Evaluating study quality, (3) GRADE assessments, (4) Meta-analysis planning.
allowed-tools	Read, Write
version	1.0.0

Risk of Bias Assessment Skill

Purpose

Systematically evaluate methodological quality and potential biases in research studies.

Tools by Study Design

RCTs: Cochrane Risk of Bias 2 (RoB 2) Non-randomized: ROBINS-I Diagnostic Studies: QUADAS-2 Prognostic Studies: QUIPS

RoB 2 Domains

Randomization Process
- Adequate sequence generation?
- Allocation concealment?
Deviations from Interventions
- Blinding effective?
- Adherence to protocol?
Missing Outcome Data
- Complete data?
- Appropriate handling?
Outcome Measurement
- Blinded assessment?
- Validated measures?
Selective Reporting
- All outcomes reported?
- Pre-registered?

Risk Levels

Low: Minimal bias
Some concerns: Potential bias
High: Serious bias likely

Integration

Use with literature-reviewer agent for systematic quality assessment of included studies.

Version: 1.0.0

risk-of-bias

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More from this repository

More from this repository

Risk of Bias Assessment Skill

Purpose

Tools by Study Design

RoB 2 Domains

Risk Levels

Integration

Risk of Bias Assessment Skill

Purpose

Tools by Study Design

RoB 2 Domains

Risk Levels

Integration