cohort-qc-thresholds
Apply cohort QC threshold reasoning to per-sample variant metrics.
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Apply cohort QC threshold reasoning to per-sample variant metrics.
Install with Codex or Claude Copy this prompt, paste it into Codex, Claude, or another assistant, and let it review the skill page and install it for you.
Based on SOC occupation classification
| name | cohort_qc_thresholds |
| title | Cohort QC Thresholds |
| description | Apply cohort QC threshold reasoning to per-sample variant metrics. |
Use this skill when interpreting per-sample cohort QC metrics. Consider call rate, missingness, heterozygosity, sex-chromosome evidence, and outlier status.
Treat thresholds as decision support, not absolute truth. Explain which metrics triggered a flag and what follow-up would confirm it.
Compare scientific variables with units, ranges, and quality caveats.
Inspect dataset structure before analysis or visualization.
Evaluate data quality from observed structure and summary evidence.
Choose visual checks that match the inspected data.
Route dataset questions to structure, analysis, or visualization experts.
Choose a plot that confirms numeric conversion integrity.