Run any Skill in Manus with one click

drugcombdb-query

Stars133

Forks4

UpdatedApril 8, 2026 at 12:05

Query canonical DrugCombDB combination records. Use when the user asks about drug pairs, synergy values, or cell-line-specific combination evidence.

Installation

Install with Codex or Claude Copy this prompt, paste it into Codex, Claude, or another assistant, and let it review the skill page and install it for you.

Run Skill in Manus

Source

QSong-github

QSong-github/DrugClaw

View GitHub Repository View Creator Repositories

Download

Run Skill in Manus

Related occupationsSOC

Based on SOC occupation classification

Biological Scientists, All OtherLife, Physical, and Social Science Occupations·SOC 19-1029

File Explorer

6 files

SKILL.md

readonly

name	drugcombdb-query
description	Query canonical DrugCombDB combination records. Use when the user asks about drug pairs, synergy values, or cell-line-specific combination evidence.

DrugCombDB Query Skill

Query canonical packaged DrugCombDB CSV rows.

Data

Path: resources_metadata/drug_combination/DrugCombDB/drugcombdb.csv
Columns: Drug1, Drug2, Cell, Synergy, SynergyType, PMID

API

Function	Input	Returns
`load_data(path)`	CSV path	`list[dict]`
`search_drug(drug_name, limit)`	drug name	`list[dict]`
`search_cell_line(cell, limit)`	cell line	`list[dict]`
`search_drug_pair(drug1, drug2, limit)`	drug pair	`list[dict]`
`search(entity, limit)`	free text	`list[dict]`
`search_batch(entities, limit)`	list of strings	`dict[str, list[dict]]`
`summarize(results, entity)`	rows + label	compact text

Usage

Run example.py directly for canonical-path demos.

More from this repository

same repository

drugcomb

QSong-github/DrugClaw

Query the DrugComb drug combination database for cancer cell-line synergy and sensitivity data. Use whenever the user asks about drug combinations, synergy scores (ZIP/Bliss/Loewe/HSA), combination sensitivity (CSS), or wants to look up how two drugs interact in a specific cancer cell line.

2026-04-08133

fda-orange-book-query

QSong-github/DrugClaw

Query or inspect the FDA Orange Book - FDA-Approved Drug Products Listing resource for drug-centric tasks with emphasis on drug knowledgebase Use whenever Codex needs the calling pattern, downloadable entrypoint, or example query flow from this skill example script.

2026-04-08133

repurposedrugs-query

QSong-github/DrugClaw

Query the RepurposeDrugs single-agent drug repurposing database. Use whenever the user asks about drug-disease repurposing associations, clinical trial phases for repurposed drugs, or wants to look up any entity (drug name, disease name, NCT ID) in RepurposeDrugs.

2026-04-08133

gdkd-query

QSong-github/DrugClaw

Query the Gene-Drug Knowledge Database (GDKD) for variant-specific gene–drug associations in oncology. Use when the user asks about cancer genomic biomarkers, drug sensitivity/resistance by gene or variant, targetable mutations, or clinical evidence for cancer therapeutics.

2026-04-08133

tarkg

QSong-github/DrugClaw

Query canonical TarKG drug-target triplets. Use when the user asks about drug-target interactions, relation labels, disease/pathway context, or quick lookups for drugs/targets in TarKG.

2026-04-08133

mecddi-query

QSong-github/DrugClaw

Query the MecDDI mechanism-based drug-drug interaction database. Use whenever the user asks about drug-drug interactions, DDI mechanisms (PK/PD), enzyme or transporter-mediated interactions, or wants to look up interacting drug pairs by drug name or MecDDI drug ID. Trigger on keywords like DDI, drug interaction, MecDDI, mechanism-based interaction, pharmacokinetic interaction, pharmacodynamic interaction, or any query involving two drugs that may interact.

2026-04-07133

Run any Skill with one click