| name | genebass-gene-burden-skill |
| description | Submit compact Genebass gene burden requests for one Ensembl gene ID and one burden set. Use when a user wants concise Genebass PheWAS summaries |
Operating rules
- Use
scripts/genebass_gene_burden.py for all Genebass calls.
- This skill accepts one Ensembl gene ID per invocation.
max_results is flexible; start around 25 for broad summaries and increase only if the user explicitly wants more associations.- Re-run requests in long conversations instead of relying on older tool output.
- Treat displayed
... in tool previews as UI truncation, not literal request content.
Execution behavior
- Return concise markdown summaries from the script JSON by default.
- Return raw JSON only if the user explicitly asks for machine-readable output.
- Supported burden sets are
pLoF, missense|LC, and synonymous, with the aliases already handled by the script.
- If the user needs the full result set, increase
max_results deliberately instead of dumping everything by default.
Input
- Read JSON from stdin as either a string Ensembl ID or an object.
- String form:
- Object form:
{"ensembl_gene_id":"ENSG00000173531","burden_set":"pLoF","max_results":25}
Output
- Success returns
ok, source, input metadata, gene, association counts, truncated, and compact associations.
- Failure returns
ok=false with error.code and error.message.
Execution
echo '{"ensembl_gene_id":"ENSG00000173531","burden_set":"pLoF","max_results":25}' | python scripts/genebass_gene_burden.py
References
- No additional runtime references are required; keep the import package limited to this file and
scripts/genebass_gene_burden.py.
