SpectrAI-Initiative/InnoClaw - Page 6

variant-cross-database-ids

Query ClinGen Allele Registry to map variant rsID to identifiers in other databases (ClinVar, gnomAD, COSMIC, UniProtKB, OMIM, etc.).

variant-functional-prediction

Query FAVOR API for variant functional prediction scores (CADD, SIFT, PolyPhen, REVEL, etc.) and gene annotation.

variant-genomic-location

Query dbSNP + NCBI Gene to get variant genomic position (chromosome, coordinates, ref/alt alleles, mutation type) and associated gene coordinates.

variant-gwas-associations

Query EBI GWAS Catalog for GWAS statistical associations (p-value, effect size, risk allele) between a variant and traits/diseases.

variant-pathogenicity

Variant Pathogenicity Assessment - Assess variant pathogenicity: Ensembl VEP prediction, ClinVar lookup, variation details, and gene phenotype associations. Use this skill for clinical genetics tasks involving get vep hgvs clinvar search get variation get…

variant-pharmacogenomics

Query PharmGKB (clinPGx) for pharmacogenomic clinical annotations — how a variant affects drug response, dosing, and adverse reactions.

variant-population-frequency

Query gnomAD for variant allele frequency across populations. Uses FAVOR to convert rsID→variant_id first, then queries gnomAD.

virtual-screening

Virtual Screening Pipeline - Virtual screening: search PubChem by substructure, compute similarity, filter by drug-likeness, and predict binding affinity. Use this skill for drug discovery tasks involving search pubchem by smiles calculate smiles similarity…

virus-genomics

Virus Genomics Analysis - Analyze virus genomics: NCBI virus dataset, annotation, taxonomy, and literature search. Use this skill for virology tasks involving get virus dataset report get virus annotation report get taxonomy search literature. Combines 4…

web-literature-mining

Scientific Literature Mining - Mine scientific literature: PubMed search, arXiv search, web search, and Tavily deep search. Use this skill for scientific informatics tasks involving pubmed search search literature search web tavily search. Combines 4 tools…

wind-site-assessment

Assess wind energy potential and perform site analysis using atmospheric science calculations.

text-to-cad

Use when the user provides a natural language description of a 3D object or mechanical part and wants to generate a CAD model. Converts the description into CadQuery Python code, automatically detects or sets up the CadQuery environment, executes the script,…

researcher-ambiguity-gate

Use when the research goal, evaluation target, scope, resources, timeline, or decision criteria are ambiguous, conflicting, or not operationally testable.

researcher-context-audit

Use when the Researcher starts, resumes, or reaches a major decision point. Build a context inventory from workstation materials, prior messages, existing artifacts, requirements, and unfinished work.

researcher-dispatch-supervisor

Use after the user confirms the plan. Dispatch the next justified worker task, supervise progress, enforce artifact-backed completion, and keep the workflow aligned with the approved plan.

researcher-plan-architect

Use when the Researcher must convert a confirmed scientific goal into a staged, executable research plan with role assignments, milestones, resources, checkpoints, and risk controls.

researcher-replan-and-recovery

Use when the workflow hits contradictions, missing evidence, failed runs, design flaws, or resource shifts. Diagnose the failure class, choose the narrowest safe correction, and escalate to the user when the core plan changes.

researcher-rigor-gate

Use before plan submission, major plan revision, and major stage transitions. Verify alignment, feasibility, rigor, completeness, and prevent unjustified regressions to earlier workflow phases.

daily-paper-roast

Use when the user wants a sharp reviewer-style critique of a batch of papers, including triage into must-read versus skippable papers, blunt per-paper criticism, or similar Chinese requests for a daily roast of papers.

paper-ai-search

Use when the user describes a research need in natural language and wants AI-assisted query expansion before searching for papers, including requests to find recent work on a topic, related papers in a direction, or similar Chinese requests for AI paper…

paper-search

Use when the user wants keyword-based academic paper discovery in Paper Study, including requests to search papers by topic, date range, or source such as arXiv, Semantic Scholar, bioRxiv, PubMed, Hugging Face daily papers, or similar Chinese requests about…