Convert raw Nanopore signal data (FAST5/POD5) to nucleotide sequences using Dorado basecaller. Covers model selection, GPU acceleration, modified base detection, and quality filtering. Use when processing raw Nanopore data before alignment. Note: Guppy is deprecated; use Dorado for all new analyses.
Meta-agent that routes bioinformatics requests to specialised sub-skills. Handles file type detection, analysis planning, report generation, and reproducibility export.
Ancestry decomposition PCA against the Simons Genome Diversity Project
Shotgun metagenomics profiling — taxonomy, resistome, and functional pathways
Semantic Similarity Index for disease research literature using PubMedBERT embeddings
Query the ClinPGx API for pharmacogenomic gene-drug data, clinical annotations, CPIC guidelines, and FDA drug labels
Medication photo to personalised PGx dosage card via Claude vision — snap a pill, get genotype-informed guidance
Compute HEIM diversity and equity metrics from VCF or ancestry data. Generates heterozygosity, FST, PCA plots, and a composite HEIM Equity Score with markdown reports.