| name | medical-meta-analysis-writing |
| description | Write medical systematic reviews and meta-analyses using a strict stepwise workflow aligned with PRISMA 2020, Cochrane, MOOSE, GRADE, and JAMA-style manuscript expectations. Use this skill when planning, screening, extracting, synthesizing, grading evidence, and drafting a publication-grade medical meta-analysis. |
Medical Meta-analysis Writing
When to Use
Use this skill when the task is to plan, execute, write, revise, or audit a medical or clinical systematic review with or without quantitative meta-analysis. This skill is designed for publication-grade work rather than generic literature summaries.
Typical triggers:
- Draft a medical SCI meta-analysis
- Plan a systematic review and meta-analysis protocol
- Build PRISMA-compliant screening and exclusion logic
- Extract study data and assess risk of bias
- Choose effect measures and synthesis structure
- Write a JAMA-style title, Key Points, abstract, and manuscript
- Stress-test a meta-analysis before submission
Default Policy
Apply these defaults unless the user explicitly overrides them:
- English-language full-text literature only
- Exclude grey literature, conference abstracts, dissertations, protocols, and preprints
- Default journal style: JAMA-like medical manuscript structure and tone
- Default review type: pairwise medical or clinical systematic review and meta-analysis
- Default interpretation style: conservative, evidence-proportionate, non-promotional
- Observational evidence should not be framed causally unless clearly justified
Workflow Gatekeeping Rules
Do not skip these gates:
Workflow Map
Follow the workflow in order:
- Topic feasibility, question framing, and protocol drafting
- Search strategy, title/abstract screening, and full-text exclusion logging
- Data extraction, risk-of-bias assessment, and pooling eligibility decisions
- Effect measure selection, primary synthesis, heterogeneity, subgroup, sensitivity, and publication-bias analysis
- GRADE certainty assessment, Summary of Findings logic, and figure/table package design
- JAMA-style front matter and full manuscript drafting
- Submission audit, reviewer simulation, and cover letter preparation
For the full dependency map, load workflow-overview.md.
Which Reference File to Load
Load only the files needed for the current stage:
- Methodological hard rules: methodology-core.md
- Workflow dependencies and stage inputs/outputs: workflow-overview.md
- Topic framing and protocol prompts: prompt-module-1-protocol.md
- Search, screening, and PRISMA prompts: prompt-module-2-search-screening.md
- Extraction, bias, and pooling-eligibility prompts: prompt-module-3-extraction-bias.md
- Statistical synthesis prompts: prompt-module-4-statistical-synthesis.md
- GRADE, Summary of Findings, and display prompts: prompt-module-5-grade-displays.md
- Title, abstract, IMRAD, and conclusion prompts: prompt-module-6-manuscript-writing.md
- Submission audit, reviewer simulation, and cover letter prompts: prompt-module-7-submission-review.md
- JAMA-facing style constraints: journal-style-jama.md
Output Standards
Unless the user asks otherwise:
- Final manuscript prose should be in English
- Working explanations and methodological reasoning may be in Chinese
- Report effect estimates with uncertainty, not p-values alone
- Distinguish pre-specified analyses from exploratory analyses
- Distinguish narrative-only inclusion from pooling-ready inclusion
- Keep claims aligned with risk of bias, heterogeneity, and GRADE certainty
- Prefer honest downgrading over overstated synthesis
