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CRISPR screen design & analysis (mirrors Claude Science's CRISPR screen skill). Designs guide libraries, runs enrichment/depletion analysis on read counts, and traces every hit back to its sgRNA support. Use for sgRNA libraries, screen counts, enrichment analysis.
Codex または Claude でインストール この Prompt をコピーして Codex、Claude、または他のアシスタントに貼り付けると、Skill ページを確認してインストールできます。
SOC 職業分類に基づく
Cheminformatics (mirrors Claude Science's cheminformatics skill). RDKit for descriptors/fingerprints/similarity and molecule drawing, ChEMBL for bioactivity, SAR/screening. Use for small molecules, SMILES, molecular descriptors, ChEMBL, medicinal chemistry. Needs the sci-bio env (rdkit).
Reproducible data analysis. Uses pandas/numpy/scipy/statsmodels for cleaning, statistics, and modeling; scripts and random seeds all land in the run, and every reported number is recomputable. Use to analyze tabular/matrix data, run statistical tests, or model.
Publication-grade figures. Uses matplotlib to generate figures from a script (never hand-drawn, never pasted from an unknown source); each figure has a rerunnable script. Layer the global CCF-Figure skill for figure conventions / top-venue layout. Use to draw paper figures and iterate to publication quality.
Provenance-backed literature review. Searches PubMed / Europe PMC / arXiv (connectors/literature.py), dedupes, synthesizes by theme, and attaches a DOI/PMID to every conclusion. Use when you need a literature review, evidence for a claim, or a related-work section.
Manuscript writing and iteration to publication quality. Organizes IMRaD structure, inserts run-generated figures/tables, manages references, and produces docx/pdf/md. Layer the global docx / doc-coauthoring / pdf skills. Use to write a paper draft, methods, results, and iterate.
Phylogenetics & evolution (mirrors Claude Science's phylogenetics skill). MAFFT alignment + IQ-TREE tree building + selection/ancestral reconstruction, results shown next to the sequences that produced them. Use for multiple-sequence alignment, phylogenetic trees, selection analysis.
| name | crispr-screen |
| description | CRISPR screen design & analysis (mirrors Claude Science's CRISPR screen skill). Designs guide libraries, runs enrichment/depletion analysis on read counts, and traces every hit back to its sgRNA support. Use for sgRNA libraries, screen counts, enrichment analysis. |
Guide design from genome annotation (
connectors/ensembl.py); enrichment via MAGeCK or an equivalent Python implementation.
