메뉴
Annotate variants with functional effects using SnpEff or Ensembl VEP, adding gene impact, population frequencies, and clinical significance.
Codex 또는 Claude로 설치 이 Prompt를 복사해 Codex, Claude 또는 다른 어시스턴트에 붙여 넣으면 Skill 페이지를 검토하고 설치를 진행할 수 있습니다.
SOC 직업 분류 기준
Decision-grade enzyme/protein mutation design for thermostability with bioactivity-preserving constraints enforced by default, plus structure-aware and consensus-ranking workflows.
Create or update repository skills that conform to local templates, provider metadata requirements, registry rules, and validation workflows.
Assess data quality by reporting missing values, outliers, sample size, and variance structure for each variable in a table.
Estimate model parameters using Bayesian inference (MCMC via Stan or PyMC), returning posterior distributions and credible intervals.
Cluster samples or features using k-means or hierarchical clustering, evaluate cluster quality with silhouette scores, and produce a dendrogram or cluster plot.
Compare a continuous variable between two groups with automatic selection of t-test, Welch test, or Mann-Whitney U test based on data properties.
| name | genome-variant-annotation |
| description | Annotate variants with functional effects using SnpEff or Ensembl VEP, adding gene impact, population frequencies, and clinical significance. |
.vcf.gz).snpeff or vep (default: snpeff).GRCh38).snpEff ann with the appropriate database (e.g., GRCh38.105), producing an annotated VCF and summary stats HTML.vep with --cache, --merged or --refseq, and add plugins (CADD, gnomAD, ClinVar, LOFTEE)..vcf.gz).hg19 when VCF is on GRCh38).