// Use when a developer asks how to get started building healthcare or life sciences agents, wants to understand the HCLS Agents Toolkit, or asks what's available in this repository. Also use when someone asks about genomics, drug discovery, clinical trials, or biomarker agents on AWS.
Use when a researcher needs to query biomedical databases for biomarker discovery, build target profiles from UniProt/Open Targets/STRING, rank biomarker candidates by evidence strength, or generate SQL queries against clinical genomic databases.
Use when orchestrating a multi-agent biomarker discovery workflow that requires coordinating database queries, pathway analysis, literature review, statistical modeling, and clinical evidence synthesis to produce ranked biomarker panels.
Use when a researcher needs to analyze biological pathways for biomarker discovery, map disease mechanisms to druggable targets using Reactome/KEGG, identify pathway enrichment from gene sets, or understand mechanism-of-action for candidate biomarkers.
Use when interpreting genomic variants from VCF files, performing clinical variant classification using ClinVar/VEP annotations, analyzing allele frequencies against population data (1000 Genomes), or generating clinical reports for genetic counseling.
Use when a developer wants to build a new healthcare or life sciences agent, structure tools and system prompts for an HCLS workflow, or create a Strands agent with domain-specific capabilities. Also use when someone asks about agent architecture, tool design, or system prompt patterns for clinical, genomics, or drug discovery use cases.
Use when a developer wants to deploy an HCLS agent to Amazon Bedrock AgentCore, configure Gateway tools as MCP endpoints, set up authentication with Cognito, configure memory, or register an agent in the AgentCore Registry. Also use for deployment troubleshooting.
| name | hcls-get-started |
| description | Use when a developer asks how to get started building healthcare or life sciences agents, wants to understand the HCLS Agents Toolkit, or asks what's available in this repository. Also use when someone asks about genomics, drug discovery, clinical trials, or biomarker agents on AWS. |
The HCLS Agents Toolkit provides three types of resources:
skills/)mcp-servers/)agents_catalog/)| Goal | Start here |
|---|---|
| Build a new HCLS agent from scratch | Use hcls-build-agent skill + agentcore_template/ |
| Deploy an existing catalog agent | Pick from agents_catalog/, follow its README |
| Connect domain tools to your IDE | Configure MCP servers from mcp-servers/ |
| Run HCLS workflows without deploying | Use skills + MCP servers directly in your assistant |
Agents are composed from:
agents_catalog/ (36+ agents across genomics, drug discovery, clinical trials, etc.)agentcore_template/ (backend) or FAST (full-stack)mcp-servers/aws-public/ and mcp-servers/third-party/)hcls-build-agent skill when ready to build a custom agenthcls-deploy-agent skill when ready to deploy to production