菜单
Compute per-sample/per-cell TF motif accessibility deviation z-scores with chromVAR (bulk, Signac, ArchR) and optionally refine TF activity with DecoupleR.
用 Codex 或 Claude 帮你安装 复制这段 Prompt，粘贴到 Codex、Claude 或其他助手里，让它检查 Skill 页面并帮你完成安装。
基于 SOC 职业分类
Load BioMaster as one integrated skill-driven bioinformatics assistant.
BioMaster conversational bioinformatics assistant; starts workflows only after execution intent or empty activation.
Automated and marker-guided single-cell cell type annotation using CellTypist, marker review, reference transfer, and confidence-aware label curation.
Ligand-receptor communication inference in single-cell or spatial data with sender-receiver summaries and cautious interpretation.
Workflow for paired or integrated single-cell RNA and ATAC analysis with multimodal latent spaces and regulatory interpretation.
Workflow for spatial transcriptomics preprocessing, domain detection, deconvolution, neighborhood analysis, and publication-ready spatial maps.
| name | bioskills-motif-deviation |
| description | Compute per-sample/per-cell TF motif accessibility deviation z-scores with chromVAR (bulk, Signac, ArchR) and optionally refine TF activity with DecoupleR. |
| domain | single-cell |
| primary_tool | chromVAR |
| methods | ["chromVAR","motifmatchr","JASPAR2024","TFBSTools","SummarizedExperiment","limma","Signac","ArchR","decoupler"] |
| macro_tags | ["workflow","motif-deviation","chromvar","tf-activity","atac"] |
| micro_tags | ["chromVAR","motifmatchr","JASPAR2024","TFBSTools","SummarizedExperiment","limma","Signac","ArchR","decoupler","qc","filtering","gc-bias","summarized-experiment","motif-matching","jaspar","cisbp","chromvar","background-peaks","deviations","variability","differential","findmarkers","marker-features","tf-activity","consensus","multi-omics"] |
| source | bioskills-motif-deviation |
| status | active |
| enabled | true |
