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Calculate protein parameters (MW, pI, extinction coefficient) and generate purification recommendations. Use when the user asks about protein properties, molecular weight, isoelectric point, extinction coefficients, or purification strategies.
用 Codex 或 Claude 帮你安装 复制这段 Prompt，粘贴到 Codex、Claude 或其他助手里，让它检查 Skill 页面并帮你完成安装。
基于 SOC 职业分类
Predict optimal construct boundaries for protein expression. Use when the user asks about domain boundaries, construct design, truncations, which region of a protein to express, or identifying disordered regions.
Manage lab notebook entries, registry items (plasmids, proteins, etc.), templates, widgets, and audit logs via the Labbook service. Use when creating or viewing lab notebook entries, managing the sample registry, or documenting experiments.
Verify open reading frames (ORFs) in plasmid sequences. Use when the user asks about verifying protein coding sequences, checking if an ORF is present in a plasmid, finding where a protein is encoded, or doing six-frame translation analysis.
Fetch sequencing data from Plasmidsaurus. Use when the user asks about listing sequencing orders, downloading sequencing results, checking order status, or retrieving plasmid sequences from Plasmidsaurus.
Design PCR primers for molecular cloning. Use when the user asks about designing primers, LIC cloning primers, sequencing primers, Gibson assembly primers, or working with NCBI accession codes for cloning.
Decision trees and workflows for molecular cloning in structural biology labs. Use when the user asks about cloning strategies, LIC vs Gibson, biGBac assembly, tag selection, expression system choice (insect vs E. coli), codon optimization, or designing constructs.
| name | protparam |
| description | Calculate protein parameters (MW, pI, extinction coefficient) and generate purification recommendations. Use when the user asks about protein properties, molecular weight, isoelectric point, extinction coefficients, or purification strategies. |
| allowed-tools | Bash(protparam_cli:*) Bash(protparam:*) |
Calculate protein biophysical parameters and generate purification recommendations.
Use the CLI at scripts/protparam_cli.py:
scripts/protparam_cli.py --sequence MKTAYIAKQRQISFVKSH...
scripts/protparam_cli.py --sequence MKTAYIAKQRQISFVKSH... --purification
scripts/protparam_cli.py --sequence MKTAYIAKQRQISFVKSH... --json
--sequence, -s: Amino acid sequence in single letter code (required)--purification, -p: Include purification recommendations--json: Output results as JSONBasic Properties
Spectroscopic Properties
Tag Detection
Cleavage Site Detection
When --purification is enabled, provides recommendations for: