biopharma-skills

Assess clinical trial design feasibility for biopharma due diligence. Evaluates patient population, biomarker prevalence, endpoint selection, comparator analysis, enrollment projections, and regulatory precedent. Use when users ask about trial design, feasibility assessment, enrollment projections, endpoint strategy, or trial success probability.

Search and analyze clinical trials for competitive intelligence. Find trials by drug, target, indication, sponsor, phase, or status. Use when users ask about clinical trials, enrollment, trial design, or competitive trial landscapes.

Comprehensive competitive intelligence for biopharma assets and indications. Analyzes competitive landscape, pipeline positioning, differentiation, and market dynamics. Use when users ask about competitive landscape, market positioning, pipeline comparison, or competitive threats.

Analyze biopharma deals (M&A, licensing, collaborations) for due diligence and competitive intelligence. Evaluates deal terms, comparables, valuations, and strategic rationale. Use when users ask about deal analysis, transaction comparables, licensing terms, M&A valuation, or deal flow.

Identify drug repurposing candidates using target-based, compound-based, and disease-driven strategies. Searches existing drugs for new therapeutic indications by analyzing targets, clinical data, safety profiles, and deal precedents. Use when exploring repurposing opportunities, new indications for approved drugs, or therapeutic alternatives.

Comprehensive computational validation of drug targets for due diligence. Evaluates targets across multiple dimensions — disease association, druggability, clinical precedent, safety, competitive landscape. Produces a quantitative Target Validation Score with GO/NO-GO recommendation. Use when users ask about target validation, druggability, or "is X a good drug target for Y?"

Systematic literature mining and evidence synthesis for biopharma research. Automates literature search, screening, data extraction, and synthesis. Use when users ask for literature reviews, evidence synthesis, publication analysis, or systematic searches on a biomedical topic.

Analyze patent landscapes for biopharma assets, targets, and therapeutic areas. Covers prior art, freedom-to-operate, patent expiry, IP positioning, and competitive IP mapping. Use when users ask about patents, IP landscape, freedom to operate, patent cliffs, or exclusivity.

Analyze biopharma company pipelines for due diligence and competitive intelligence. Maps pipeline assets by phase, indication, target, and modality. Identifies pipeline gaps, concentration risks, and strategic positioning. Use when users ask about company pipelines, pipeline comparison, portfolio analysis, or R&D strategy assessment.

Regulatory intelligence for biopharma due diligence and strategy. Covers FDA/EMA approvals, regulatory pathways, advisory committees, PDUFA dates, breakthrough/fast track designations, and biosimilar/generic entry. Use when users ask about regulatory status, approval timelines, FDA filings, regulatory strategy, or agency interactions.