| name | tooluniverse-adverse-outcome-pathway |
| description | Map environmental and industrial chemicals to adverse outcome pathways (AOPs) — molecular initiating event to organ-level toxicity. Uses AOPWiki, GHS classification, IARC carcinogen status, and LD50 data. Use for environmental/industrial chemical risk assessment, regulatory-grade hazard characterization, and AOP stressor mapping. Distinct from drug-safety analysis (use tooluniverse-pharmacovigilance for drugs). |
| disable-model-invocation | true |
Adverse Outcome Pathway & Regulatory Risk Assessment
Distinct from drug safety (see tooluniverse-toxicology): this skill targets environmental and
industrial chemicals where the focus is AOP stressor mapping, GHS classification, LD50 hazard
quantification, and IARC carcinogen status — not FAERS signals or FDA drug labels.
When to Use
Apply when researcher asks about:
- "What AOPs are associated with [pesticide/solvent/industrial chemical]?"
- "What is the GHS hazard classification for [compound]?"
- "What is the LD50 for [compound]?"
- "Is [compound] a carcinogen (IARC classification)?"
- "Which genes does [chemical] interact with (CTD)?"
- "Regulatory risk assessment for [environmental chemical]"
- "What diseases are associated with [chemical] exposure?"
Do NOT use for FDA-approved drugs with FAERS data — use tooluniverse-toxicology instead.
Key Tools
| Tool | Purpose | Key Params |
|---|
AOPWiki_list_aops |
