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Analyse 10x Visium spatial transcriptomics: SpaceRanger outs or spatial h5ad in, then QC, Leiden clustering, Wilcoxon markers, Moran's I, neighbourhood enrichment and co-occurrence in one local report.
لغة النص الأصلي: الإنجليزية
Population genetics of pre-aligned DNA sequences or multi-sample VCFs using selected DnaSP 6 methods. Use for diversity, neutrality statistics, linkage disequilibrium, InDel polymorphism, divergence, MK, Ka/Ks and codon usage; not alignment, phasing or…
لغة النص الأصلي: الإنجليزية
Pharmacogenomic report from DTC genetic data (23andMe/AncestryDNA) — 12 genes, 31 SNPs, 51 drugs
لغة النص الأصلي: الإنجليزية
Personalised nutrition report from consumer genetic data (23andMe, AncestryDNA, VCF) — interrogates nutritionally-relevant SNPs and generates actionable dietary guidance, all computed locally.
لغة النص الأصلي: الإنجليزية
Search, browse, and retrieve scientific protocols from protocols.io via REST API. Client token authentication for private protocols. Use when user mentions protocols.io, lab protocols, DOI lookup, protocol search, protocol steps, or scientific methods.
لغة النص الأصلي: الإنجليزية
Query and display Labstep electronic lab notebook data — experiments, protocols, resources, and inventory — via labstepPy. Supports offline demo mode with synthetic biology data.
لغة النص الأصلي: الإنجليزية
Calculate polygenic risk scores from DTC genetic data using the PGS Catalog
لغة النص الأصلي: الإنجليزية
End-to-end WGS to polygenic risk score pipeline. Takes paired-end FASTQ files (or a pre-existing VCF) through nf-core/sarek for variant calling, applies VCF QC (normalisation, hard filtering, Ti/Tv and Het/Hom checks), then computes polygenic risk scores via…
لغة النص الأصلي: الإنجليزية
Unified personal genomic profile report — reads a PatientProfile JSON and synthesizes all skill results into a single "Your Genomic Profile" document.
لغة النص الأصلي: الإنجليزية
Infers genetic super-population ancestry from a 23andMe/AncestryDNA file and computes ancestry-stratified odds ratios with an exploratory Ancestry Elevation Score (AES) showing where ancestry-specific GWAS effect sizes diverge from European reference…
لغة النص الأصلي: الإنجليزية
Import DRAGEN-exported Illumina result bundles into ClawBio for local tertiary analysis and downstream routing.
لغة النص الأصلي: الإنجليزية
Wrapper skill for running nf-core/rnastructurome — chemical-probing RNA structure analysis (SHAPE/DMS, RT-stop/MaP readout) from FASTQ to per-base reactivity, secondary-structure predictions, and 2D diagrams.
لغة النص الأصلي: الإنجليزية
Scaffold a new ClawBio skill from a spec file (JSON/YAML) or interactively — generates SKILL.md, Python skeleton, tests, and updates catalog.json
لغة النص الأصلي: الإنجليزية
Federated variant lookup across 8 genomic databases — GWAS Catalog, Open Targets, PheWeb (UKB, FinnGen, BBJ), GTEx, and more.
لغة النص الأصلي: الإنجليزية
Fast genomic interval operations (overlap, nearest, merge, coverage, cluster, complement, subtract, count-overlaps), multi-format bioinformatics I/O, DataFusion SQL, and pileup on Polars DataFrames via polars-bio. A scalable bioframe/bedtools alternative.
لغة النص الأصلي: الإنجليزية
Aggregate public target-level evidence across omics and translational sources for research triage.
لغة النص الأصلي: الإنجليزية
Fetch a region of cis-eQTL summary statistics from EBI eQTL Catalogue v7+ via tabix-on-FTP. Use when an agent needs eQTL beta / SE / p-value for every variant in a window around a gene's TSS for one specific dataset (study × tissue × quantification method).…
لغة النص الأصلي: الإنجليزية
Fetch a region of GWAS summary statistics from the NHGRI-EBI GWAS Catalog harmonised collection via tabix-on-FTP. Use when an agent needs GWAS beta / SE / p-value for every variant in a window for one specific study (GCST accession). Input: accession,…
لغة النص الأصلي: الإنجليزية
Compute pairwise r² between a lead variant and every variant in a window using the 1000 Genomes Phase 3 GRCh38 reference panel, ancestry-stratified. Use when an agent needs LD coloring for a regional plot or LD pruning around a candidate causal variant.…
لغة النص الأصلي: الإنجليزية
Render a 4-panel regional LocusCompare diagnostic for one (lead variant, exposure study, outcome study) tuple - overlays GWAS Manhattan, QTL Manhattan, GENCODE gene track, and cross-trait scatter colored by LD r². Use when an agent needs visual confirmation…
لغة النص الأصلي: الإنجليزية
ClawBio wrapper around nf-core/sarek 3.8.1 covering mapping through annotation for germline, tumor-only, and somatic paired analyses.
لغة النص الأصلي: الإنجليزية
Wrapper skill for running nf-core/scrnaseq 4.1.0 upstream single-cell RNA-seq preprocessing from FASTQ with strict preflight, reproducibility outputs, and downstream handoff to ClawBio scRNA skills.
لغة النص الأصلي: الإنجليزية
Fetch a regional slice of plasma pQTL summary statistics from the UK Biobank Pharma Proteomics Project (UKB-PPP; Sun 2023 Nature) for a specific (protein, ancestry) measurement. Use when an agent needs per-variant beta / SE / p-value around a coloc-lead…
لغة النص الأصلي: الإنجليزية
Galaxy tool discovery, intelligent recommendation, and execution — 8,000+ bioinformatics tools from usegalaxy.org with multi-signal scoring and workflow suggestions
لغة النص الأصلي: الإنجليزية
Flow.bio API bridge — authenticate, browse pipelines/samples/projects, search, upload data, launch pipeline executions, and check run status on any Flow instance.
لغة النص الأصلي: الإنجليزية
Differential expression analysis for bulk RNA-seq and pseudo-bulk count matrices with QC, PCA, and contrast testing.
لغة النص الأصلي: الإنجليزية
Cell segmentation in fluorescence microscopy images. Supports Cellpose/cpsam (Cellpose 4.0) with additional backends planned. Produces segmentation masks, per-cell morphology metrics (area, diameter, centroid, eccentricity), overlay figures, and a report.md.
لغة النص الأصلي: الإنجليزية
Semantic search across UK Biobank's 12,000+ data fields and publications — find the right variables for your research question.
لغة النص الأصلي: الإنجليزية
Phylogenetic distance matrices and trees from VCF or FASTA data using the fastreeR hybrid Java/Python toolkit (VCF2TREE, VCF2DIST, DIST2TREE, FASTA2DIST).
لغة النص الأصلي: الإنجليزية
Deterministic multi-sample QC triage for identity, sex, contamination, and batch-shift outliers
لغة النص الأصلي: الإنجليزية
Analyze a single FASTA file (nucleotide or protein), compute sequence-level metrics (GC, ORFs, MW, pI, GRAVY, secondary-structure fractions) with Biopython, and write a Markdown report plus structured JSON for downstream chaining.
لغة النص الأصلي: الإنجليزية
Deterministic CRISPR screen hit ranking from local guide-level count tables
لغة النص الأصلي: الإنجليزية
Deterministic marker-dominance region mapping from local spot-count CSVs
لغة النص الأصلي: الإنجليزية
Blood RNA-seq expression-outlier detection for rare-disease diagnostics. Cases scored against a control reference panel; outliers ranked and filtered by a haploinsufficient disease-gene panel.
لغة النص الأصلي: الإنجليزية
Statistical fine-mapping of GWAS loci using SuSiE, SuSiE-inf, and Approximate Bayes Factors to identify credible sets and posterior inclusion probabilities (PIPs) for causal variant discovery. SuSiE-inf adds an infinitesimal polygenic component for improved…
لغة النص الأصلي: الإنجليزية
End-to-end ML phylogenetic tree inference — MSA, trimming, ModelFinder, IQ-TREE2/RAxML-NG.
لغة النص الأصلي: الإنجليزية
Find clinical trials for a gene, variant, or condition from ClinicalTrials.gov + EUCTR, with FHIR R4 output
لغة النص الأصلي: الإنجليزية
Two-sample Mendelian Randomisation from GWAS summary statistics with IVW, MR-Egger, weighted median/mode, and full sensitivity analysis (Cochran Q, Egger intercept, Steiger, F-statistic, leave-one-out).
لغة النص الأصلي: الإنجليزية
Meta-agent that routes bioinformatics requests to specialised sub-skills. Handles file type detection, analysis planning, report generation, and reproducibility export.
لغة النص الأصلي: الإنجليزية
Search PubMed, preserve complete abstracts and sections, and produce research briefings with abstract openings or optional OpenAI/Ollama summaries.
لغة النص الأصلي: الإنجليزية
انسخ هذا الطلب إلى المساعد الذكي الذي تستخدمه.
Follow https://skillsmp.com/skill-install/prompt.md to install Agent Skills from https://github.com/ClawBio/ClawBio.تعذر تحميل ملف README. لا يزال بإمكانك استكشاف مهارات المستودع أدناه.