| name | borzoi |
| description | Use Borzoi-style regulatory genomics models for sequence-to-expression or variant-effect analysis. Use when the task asks for noncoding variant impact, regulatory sequence design, or expression prediction. |
Borzoi
Use this skill for regulatory genomics modeling around sequence, variant, and expression effects.
Workflow:
- Pin genome build, interval coordinates, reference/alternate alleles, cell type or tissue, strand, and window size.
- Confirm the model route: local checkpoint, managed endpoint, notebook package, or external documented service. Record missing checkpoints as setup work, not as a completed model run.
- Build input FASTA/variant manifests with source URLs or accession IDs.
- Save prediction arrays, summary tables, plots, model version, and runtime metadata as Feynman artifacts.
- Compare predicted effects against GTEx, ENCODE, literature, or other source-backed evidence when available.
Keep source-owned genomic coordinates separate from model-owned effect predictions in every output.
