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جمع SkillsMP عدد ٢٩ من skills من JimLiu/science-skills. افتح أي skill لمراجعة مصدره وتفاصيله.
عرض ٢٩ من أصل ٢٩ skills مجمعة.
Predict protein structure for monomers and multimers with AlphaFold2 via the ColabFold runner (Mirdita et al. 2022, github.com/sokrypton/ColabFold; AlphaFold2 Jumper et al. 2021). Reach for this skill to fold a sequence or complex with the AF2/AF2-Multimer…
لغة النص الأصلي: الإنجليزية
Structure prediction for protein, nucleic-acid, and small-molecule complexes with Boltz-2 (Passaro & Wohlwend et al. 2025, github.com/jwohlwend/boltz). Reach for this skill to validate designed binders against a target, to co-fold a protein with a SMILES or…
لغة النص الأصلي: الإنجليزية
Predict genome-wide functional tracks (RNA-seq, CAGE, DNase, ChIP) from DNA sequence with Borzoi. Use this skill when: (1) Scoring the regulatory effect of a variant on expression/accessibility, (2) Generating predicted coverage tracks for a locus, (3)…
لغة النص الأصلي: الإنجليزية
Structure prediction for protein, nucleic-acid, and small-molecule complexes with the Chai-1 foundation model (Chai Discovery 2024, github.com/chaidiscovery/chai-lab). Reach for this skill to predict an antibody-antigen or protein-ligand complex from a single…
لغة النص الأصلي: الإنجليزية
Set up a compute environment on a remote provider so Claude Science jobs can run there. Covers direct SSH/conda hosts, Slurm clusters, container-via-bridge runners, and managed-API providers (Modal, GCP, RunPod). Use when standing up a new provider, porting…
لغة النص الأصلي: الإنجليزية
Create, configure, and maintain custom agent profiles and author new skills via the `repl` tool. Use when the user wants to create an agent profile, build a custom agent, modify agent capabilities, attach or detach skills/connectors on a profile, author a…
لغة النص الأصلي: الإنجليزية
Predict small-molecule binding poses with DiffDock-L (Corso et al. 2023/2024, github.com/gcorso/DiffDock) — blind diffusion docking that places a ligand into a protein pocket without a predefined search box and ranks the samples with a learned confidence…
لغة النص الأصلي: الإنجليزية
Biohub ESMFold2 / ESMFold2-Fast all-atom co-folding (Candido et al. 2026, github.com/Biohub/esm). Single-sequence and MSA modes; protein, DNA, RNA, ligand (CCD/SMILES), modified residues. FoldBench Ab-Ag 50-55%, PPI 70-77% DockQ-pass. Also covers the…
لغة النص الأصلي: الإنجليزية
Score, embed, and generate DNA sequences with Evo 2, a long-context genomic foundation model. Use this skill when: (1) Computing per-nucleotide or per-sequence likelihoods for variant effect scoring, (2) Embedding genomic windows for downstream…
لغة النص الأصلي: الإنجليزية
Embed proteins with Meta AI's ESM-2 (`fair-esm` package). Use this skill when: (1) Extracting per-residue or per-sequence embeddings for downstream ML, (2) Masked-LM likelihood / mutation effect scoring, (3) Contact prediction from a sequence.
لغة النص الأصلي: الإنجليزية
Compose one publication-grade multi-panel figure. Entry from a one-line claim + data refs, OR from an existing figure via `derive_outline(png)`. Runs a per-figure loop: outline (12-col grid, per-panel ask + label_budget) → fan-out one sub-agent per panel…
لغة النص الأصلي: الإنجليزية
Publication-grade figure correctness and legibility rules. Load before drawing any plot and call `apply_figure_style()` — sets a role-mapped font-size ladder, outward ticks, frameless legends, and 300-dpi output. The skill is a checklist, not a house look:…
لغة النص الأصلي: الإنجليزية
Generate a therapeutic indication dossier. Covers the patient population, epidemiology, disease biology, standard of care, regulatory precedent, and landmark clinical trials.
لغة النص الأصلي: الإنجليزية
Inverse-fold a backbone with ligand, nucleic-acid, and metal context using LigandMPNN (Dauparas et al. 2023, github.com/dauparas/LigandMPNN). Reach for this skill to redesign the residues lining a binding pocket around a bound small molecule or cofactor, to…
لغة النص الأصلي: الإنجليزية
Find, verify, and synthesize scientific literature — from "what's the seminal paper for X" through full multi-source reviews. Covers grounding claims in real retrieved sources, avoiding fabricated citations, handling retractions, and calibrating confidence to…
لغة النص الأصلي: الإنجليزية
Register a model service in the managed family — a local model server container the daemon starts/stops on demand, or a remote upstream model API (https). Read the runbook, allocate a port (local only), compose idempotent start/stop scripts (local only),…
لغة النص الأصلي: الإنجليزية
Structure prediction using OpenFold3, an open-weights PyTorch reproduction of AlphaFold3 from the AlQuraishi Lab. Use this skill when predicting protein/nucleic-acid/ligand complex structures with an Apache-2.0-licensed AF3 reimplementation.
لغة النص الأصلي: الإنجليزية
Judge and reshape the STORY a paper's figures tell. Input is the work itself — manuscript (or abstract) + figure deck — no hand-written brief. `derive_paper_brief(abstract, captions)` extracts pitch/vision/per-figure-claims; a handling-editor reviewer on the…
لغة النص الأصلي: الإنجليزية
Use this skill when the user has attached a PDF, paper, report, or other document and the answer needs content from more than one place in it: summarize the methods or any other section, compare sections, find where a topic is discussed, read a value or label…
لغة النص الأصلي: الإنجليزية
Stop and consult this skill whenever your response would include specific facts about Anthropic's products. Covers: Claude Code (how to install, Node.js requirements, platform/OS support, MCP server integration, configuration), Claude API (function…
لغة النص الأصلي: الإنجليزية
Inverse-fold a protein backbone (PDB structure) into amino-acid sequence with ProteinMPNN (Dauparas et al. 2022, github.com/dauparas/ProteinMPNN). Reach for this skill to run sequence design on RFdiffusion backbones, to redesign one chain of a PDB while…
لغة النص الأصلي: الإنجليزية
Run GPU jobs on the user's own Modal account via host.compute.create('byoc:modal', ...). Covers the create→submit→wait_for_notification flow, the compute_provider kernel for env setup, image/volume resolution, and the two approval cards. Load once you've…
لغة النص الأصلي: الإنجليزية
Submit→wait_for_notification→harvest workflow for the user's SSH/SLURM hosts. Load once you've decided to dispatch remote.
لغة النص الأصلي: الإنجليزية
Embed and annotate single-cell expression data with scGPT, a foundation model for single-cell biology. Use this skill when: (1) Producing cell embeddings from an AnnData for clustering/integration, (2) Zero-shot or fine-tuned cell-type annotation, (3)…
لغة النص الأصلي: الإنجليزية
Probabilistic single-cell RNA-seq with scvi-tools — scVI for a batch-corrected latent space, scANVI for semi-supervised label transfer, and Bayesian differential expression. Reach for this skill to integrate scRNA-seq batches, embed cells for clustering,…
لغة النص الأصلي: الإنجليزية
Claude Science's own session database schema and SDK surface for introspection via host.query(). Load this when you need to query your own conversation history, token usage, cost accounting, execution log, or artifact metadata beyond what…
لغة النص الأصلي: الإنجليزية
Create new skills, modify and improve existing skills, and measure skill performance. Use when users want to create a skill from scratch, edit, or optimize an existing skill, run evals to test a skill, benchmark skill performance with variance analysis, or…
لغة النص الأصلي: الإنجليزية
Inverse-fold a backbone with SolubleMPNN — ProteinMPNN retrained on a soluble-PDB subset (Dauparas et al. 2022) — for sequences biased toward cytosolic expression and reduced aggregation. Reach for this skill when designs from vanilla ProteinMPNN are…
لغة النص الأصلي: الإنجليزية
Call a registered model endpoint over its native HTTP API from the endpoint's scoped inference kernel (BASE_URL preloaded). Load once a task needs predictions from a registered model endpoint.
لغة النص الأصلي: الإنجليزية