ksb-d08-k0014

name	KSB-D08-K0014
description	Network Analysis and Graph Theory: Drug-event relationship mapping, polypharmacy interaction detection, patient journey analysis, tempo...
version	1.0.0
domain	D08
domain_name	Signal Detection & Management
type	Knowledge
proficiency_level	L4
bloom_level	analyze
triggers	["explain network analysis and graph theory","what is network analysis and graph theory","analyze network analysis and graph theory"]
epa_mapping	EPA-04, EPA-05
cpa_mapping	CPA-02
regulatory_refs	FDA-GUID-006, EMA-GVP-005, EMA-GVP-010, CIOMS-VIII

KSB-D08-K0014: Network Analysis and Graph Theory

Overview

Domain: D08 - Signal Detection & Management Type: Knowledge Proficiency Level: L4 (Proficient - Independent practice) Bloom Level: Analyze

Description

Drug-event relationship mapping, polypharmacy interaction detection, patient journey analysis, temporal network evolution

Context

• Major Section: Signal Detection Theoretical Foundation and Methodological Framework
• Section: Advanced AI-Enhanced Detection Algorithms

EPA Mapping

• EPA-04:3009-3010
• EPA-05:3011-3012

CPA Pathway

• CPA-02

Regulatory References

• FDA-GUID-006
• EMA-GVP-005
• EMA-GVP-010
• CIOMS-VIII

Instructions

When this skill is activated, Claude should:

1. Demonstrate L4 proficiency in network analysis and graph theory
2. Apply analyze level cognitive skills to analyze the topic
3. Reference relevant regulatory guidance (FDA-GUID-006, EMA-GVP-005, EMA-GVP-010, CIOMS-VIII)
4. Connect to related EPAs: EPA-04, EPA-05

Key Competencies

• Drug-event relationship mapping, polypharmacy interaction detection, patient journey analysis, temporal network evolution

Assessment Criteria

• Can analyze core concepts independently
• Demonstrates understanding of regulatory context
• Applies knowledge appropriately to PV scenarios

Related Skills

• Other D08 skills in Advanced AI-Enhanced Detection Algorithms
• Cross-domain integrations per DAG architecture

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Generated from PV KSB Framework v1.0 | 2025-12-31