| name | pathway_lookup |
| description | Look up pathway or GO/Reactome/KEGG term definitions and key genes. |
| category | bio/literature |
| version | 1 |
| requires_tools | ["fetch_url","search_knowledge_base"] |
| requires_network | true |
| user_invocable | true |
| species | any |
| modality | literature |
| stage | utilities |
| stability | experimental |
| safety_level | low |
Pathway Lookup
When to use
User asks what a pathway or GO/Reactome/KEGG term is, or which genes are in it.
Inputs
- term: Pathway or term name or ID (e.g. "apoptosis", "GO:0006915", "R-HSA-109581")
Steps
-
Local first: Use search_knowledge_base with the term to find lab-curated definitions.
-
Online: Use fetch_url for public APIs:
- Reactome:
https://reactome.org/ContentService/data/pathway/{id}/containedGenes or search.
- GO: Quick description via EBI or geneontology.org if needed.
- KEGG: Optional if you have a stable API.
-
Synthesize: Definition of the pathway/term + list of key genes (if available) + optional link.
Output format
- Term/ID
- Definition (1–3 sentences)
- Key genes (if available)
- Source / link
Failure modes
- Unknown term: report "No definition found; check ID or try alternate name."