choxos/BiostatAgent - Page 2

time-series-models

Bayesian time series models including AR, MA, ARMA, state-space models, and dynamic linear models in Stan and JAGS.

clinical-trial-design-patterns

Common clinical trial design patterns including multi-arm, multi-endpoint, adaptive, and stratified designs. Use when selecting or implementing trial designs.

multiplicity-methods

Multiple testing procedures reference for clinical trials. Use when selecting or implementing multiplicity adjustments, gatekeeping procedures, or graphical approaches.

power-optimization-patterns

Direct and tradeoff-based optimization strategies for clinical trial design. Use when optimizing sample size, selecting design parameters, or performing sensitivity analysis.

time-to-event-methods

Survival analysis methods including weighted logrank, MaxCombo, RMST, and milestone tests. Use when analyzing TTE data or choosing analysis methods for non-proportional hazards.