cx-bindcraft-binder-design

Run a pinned BindCraft campaign for de novo protein binders using AlphaFold2 optimization, ProteinMPNN, PyRosetta, and configurable filters. Use only when the target structure, hotspot strategy, candidate budget, dependency licenses, and experimental handoff are explicit.

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Repository: eightmm/codex-science
Last source activity: July 10, 2026 at 13:08
Detected SKILL.md language: English
Stars: 2
Forks: 0

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quantitative-research

Execute auditable quantitative research across preregistered study design, statistical inference, numerical verification, dimensional analysis, uncertainty propagation, counterexample search, and formal proof. Use when a scientific or mathematical question needs actual computation and machine-readable evidence rather than only explanation.

2026-08-04

statistical-decision-analysis

Compare finite actions under uncertainty with explicit states, loss, utility or risk-neutral payoff, priors, experiment likelihoods, and a declared decision criterion. Use for Bayes risk, expected utility or payoff, pure-action minimax, minimax regret, dominance, posterior decision policies, EVPI/EVSI, experiment-cost decisions, and prior-threshold sensitivity; do not use for ordinary statistical testing, causal identification, strategic games, or MDP/POMDP/RL planning.

2026-08-04

cx-statistical-decision-analysis

2026-08-04

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name	cx-bindcraft-binder-design
description	Run a pinned BindCraft campaign for de novo protein binders using AlphaFold2 optimization, ProteinMPNN, PyRosetta, and configurable filters. Use only when the target structure, hotspot strategy, candidate budget, dependency licenses, and experimental handoff are explicit.