| name | mouse-colony-planner |
| description | Calculate breeding timelines and cage requirements for transgenic mouse colonies |
| version | 1.0.0 |
| category | Wet Lab |
| tags | [] |
| author | AIPOCH |
| license | MIT |
| status | Draft |
| risk_level | Medium |
| skill_type | Tool/Script |
| owner | AIPOCH |
| reviewer | |
| last_updated | 2026-02-06 |
Mouse Colony Planner
Calculate timelines and cage numbers required for transgenic mouse breeding to optimize breeding costs.
Functions
- Timeline Calculation: Calculate time required for each stage based on breeding scheme
- Cage Planning: Estimate cage numbers needed for experiments
- Cost Estimation: Calculate total breeding costs (cage fees, husbandry fees, genotyping fees, etc.)
Usage
Command Line
python scripts/main.py --scheme <breeding_scheme> --females <number_of_females> --males <number_of_males> [options]
Parameters
| Parameter | Description | Default |
|---|
--scheme | Breeding scheme: heterozygote, homozygote, conditional | Required |
--females | Starting number of females | Required |
--males | Starting number of males | Required |
--gestation | Gestation period (days) | 21 |
--weaning | Weaning age (days) | 21 |
--sexual-maturity | Sexual maturity age (days) | 42 |
--cage-capacity | Maximum cage capacity | 5 |
--cage-cost | Cage cost per day (CNY) | 3.0 |
--genotyping-cost | Genotyping cost per mouse (CNY) | 15.0 |
--target-pups | Target number of specific genotype mice | 10 |
Breeding Scheme Descriptions
- heterozygote (Heterozygote breeding): Heterozygote x Wild type → 50% Heterozygotes
- homozygote (Homozygote breeding): Heterozygote x Heterozygote → 25% Homozygotes
- conditional (Conditional knockout): Requires two-step breeding, introducing Cre/loxp system