SNP Functional Impact Analysis - Analyze SNP function: VEP prediction, variation details, phenotype association, and literature evidence. Use this skill for functional genomics tasks involving get vep id get variation get phenotype accession pubmed search.…
Skills in this repository
InternScience/DrClaw - Page 11
SkillsMP has collected 477 skills from InternScience/DrClaw. Open a skill to review its source and details.
InternScience/DrClawShowing 40 of 477 collected skills.
Retrieve gene expression data from TCGA (The Cancer Genome Atlas) to analyze cancer-specific expression patterns.
Tissue-Specific Expression Analysis - Analyze tissue-specific expression: ChEMBL tissue data, TCGA cancer expression, Ensembl gene info, and NCBI gene data. Use this skill for tissue biology tasks involving get tissue by id get gene expression across cancers…
Transcriptome Analysis Pipeline - Analyze transcriptome: Ensembl transcript lookup, sequence retrieval, haplotype analysis, and UCSC track data. Use this skill for transcriptomics tasks involving get lookup id get sequence id get transcript haplotypes get…
UCSC Genome Browser Exploration - Explore genome via UCSC: list genomes, list tracks, get sequence, get track data, and cytoband info. Use this skill for genomics tasks involving list genomes list tracks get sequence get track data get cytoband. Combines 5…
Query NCBI ClinVar for variant clinical pathogenicity classification (Pathogenic/Benign/VUS), review status and associated diseases.
Query ClinGen Allele Registry to map variant rsID to identifiers in other databases (ClinVar, gnomAD, COSMIC, UniProtKB, OMIM, etc.).
Query FAVOR API for variant functional prediction scores (CADD, SIFT, PolyPhen, REVEL, etc.) and gene annotation.
Query dbSNP + NCBI Gene to get variant genomic position (chromosome, coordinates, ref/alt alleles, mutation type) and associated gene coordinates.
Query EBI GWAS Catalog for GWAS statistical associations (p-value, effect size, risk allele) between a variant and traits/diseases.
Variant Pathogenicity Assessment - Assess variant pathogenicity: Ensembl VEP prediction, ClinVar lookup, variation details, and gene phenotype associations. Use this skill for clinical genetics tasks involving get vep hgvs clinvar search get variation get…
Query gnomAD for variant allele frequency across populations. Uses FAVOR to convert rsID→variant_id first, then queries gnomAD.
Virus Genomics Analysis - Analyze virus genomics: NCBI virus dataset, annotation, taxonomy, and literature search. Use this skill for virology tasks involving get virus dataset report get virus annotation report get taxonomy search literature. Combines 4…
Calculate buoyancy forces and acceleration for fluid mechanics and hydrodynamics analysis.
Calculate electrical capacitance from geometric parameters and dielectric properties for circuit design.
Electrical Circuit Analysis - Analyze electrical circuit: compute capacitance, convert resistance units, calculate total charge, and duty cycle. Use this skill for electrical engineering tasks involving convert resistance kOhm to Ohm calculate geometric term…
Electromagnetic Field Analysis - Analyze EM fields: vacuum permittivity, total charge, radiation pressure, and photon calculations. Use this skill for electromagnetics tasks involving calculate vacuum permittivity calculate total charge calculate radiation…
Energy Unit Conversion Pipeline - Convert between energy units and analyze: MeV to Joules, scientific notation, and error calculation. Use this skill for physics tasks involving convert energy MeV to J convert to scientific notation format scientific notation…
Experimental Data Processing - Process experimental data: absolute error, mean square, max value, scientific notation formatting. Use this skill for experimental physics tasks involving calculate absolute error calculate mean square calculate max value format…
Calculate volumes of geometric shapes for engineering design and mathematical analysis.
Geometry & Trigonometry Suite - Solve geometry problems: calculate area, height from sine, angle in degrees, and increase factor. Use this skill for mathematics tasks involving calculate area calculate height from length and sine calculate phi deg calculate…
Length & Dimension Measurement - Precision length measurement: convert mm to m, calculate length plus width, area, and error. Use this skill for metrology tasks involving convert length mm to m calculate length plus width calculate area calculate absolute…
Analyze measurement errors, uncertainties, and statistical variations in experimental data for quality control.
Charge Carrier Mobility Analysis - Analyze carrier mobility: calculate new mobility, compute vacuum permittivity, and error analysis. Use this skill for semiconductor physics tasks involving calculate new mobility calculate vacuum permittivity calculate…
Nuclear Physics Calculations - Nuclear physics: energy conversion MeV to J, calculate total power, photon rate, and error analysis. Use this skill for nuclear physics tasks involving convert energy MeV to J calculate total power calculate incident photon rate…
Calculate optical frequency and wavelength relationships for photonics and electromagnetic analysis.
Optical System Analysis - Analyze optical system: calculate photon rate, frequency range, radiation pressure, and electron wavelength. Use this skill for optics tasks involving calculate incident photon rate calculate frequency range calculate radiation…
Signal Processing Analysis - Analyze signals: duty cycle, frequency range, electron wavelength, and measurement error analysis. Use this skill for signal processing tasks involving calculate duty cycle calculate frequency range electron wavelength calculate…
Statistical Error Analysis - Analyze measurement errors: absolute error, scientific notation, max value, mean square, and formatting. Use this skill for statistics tasks involving calculate absolute error convert to scientific notation calculate max value…
Thermal & Heat Transfer Analysis - Analyze thermal system: calculate heat released, convert energy units, compute potential energy, and dynamic viscosity. Use this skill for thermal engineering tasks involving calculate heat released convert energy MeV to J…
Multi-Unit Conversion Suite - Convert units across domains: length mm to m, radius m to cm, dimensions to meters, nm to um, volume to cm3. Use this skill for metrology tasks involving convert length mm to m convert radius m to cm convert dimensions to meters…
AlphaFold Structure Analysis Pipeline - AlphaFold pipeline: download predicted structure, predict pockets, extract sequence, and compute properties. Use this skill for computational biology tasks involving download alphafold structure run fpocket extract pdb…
Antibody-Target Analysis - Analyze an antibody target: UniProt protein info, InterPro domains, protein properties, and biotherapeutic data from ChEMBL. Use this skill for immunology tasks involving get uniprotkb entry by accession query interpro…
Binding Site Characterization - Characterize binding sites: predict pockets with fpocket and P2Rank, get binding site info from ChEMBL, and visualize. Use this skill for structural biology tasks involving run fpocket pred pocket prank get binding site by id…
BLAST & Protein Analysis Pipeline - BLAST search followed by comprehensive protein analysis: BLAST, then structure prediction, properties, and function. Use this skill for sequence bioinformatics tasks involving blast search pred protein structure esmfold…
Computational Analysis via Code Execution - Execute custom computational analysis code, analyze software, and search for reference implementations. Use this skill for computational science tasks involving exec code software analysis search dataset search…
Comprehensive protein analysis combining InterProScan domain identification with BLAST similarity search to provide complete functional and evolutionary annotation.
Disease Protein Profiling - Profile a disease protein: UniProt data, AlphaFold structure, InterPro domains, phenotype associations from Ensembl. Use this skill for medical proteomics tasks involving query uniprot download alphafold structure query interpro…
Analyze DNA and RNA sequences including molecular weight calculation, reverse complement generation, and oligonucleotide properties.
Enzyme Active Site Engineering - Engineer enzyme: identify active site residues, predict pocket, analyze binding site, and predict mutations. Use this skill for enzymology tasks involving predict functional residue run fpocket get binding site by id pred…