Analyzes spatial transcriptomics with squidpy (1.8.x) on AnnData and SpatialData objects, routing platforms correctly: Visium spots use spatial_neighbors(coord_type='grid') and pair with deconvolution, while Xenium/MERFISH single-cell data use…
Skills in this repository
TuYv/ccpm - Page 18
SkillsMP has collected 5,252 skills from TuYv/ccpm. Open a skill to review its source and details.
TuYv/ccpmShowing 40 of 5,252 collected skills.
Store and query genomic variant data at scale with TileDB-VCF — ingest VCF/BCF into compressed TileDB arrays, add samples incrementally, run fast parallel region/sample queries, and export back to VCF. Use when managing population-genomics variant datasets…
Builds PyTorch-native graph neural networks with TorchDrug for molecules and proteins, exposing custom GNN architectures, task/dataset abstractions, molecular generation, retrosynthesis planning, and knowledge-graph reasoning. Use when developing custom graph…
Generates concise (3-4 page), focused medical treatment plans in LaTeX/PDF format across all clinical specialties — general medical treatment, rehabilitation therapy, mental health care, chronic disease management, perioperative care, and pain management —…
Reference for the Claude API / Anthropic SDK — model ids, pricing, params, streaming, tool use, MCP, agents, caching, token counting, model migration. TRIGGER — read BEFORE opening the target file; don't skip because it "looks like a one-liner" — whenever:…
Guidance for distinctive, intentional visual design when building new UI or reshaping an existing one. Helps with aesthetic direction, typography, and making choices that don't read as templated defaults.
Replace with description of the skill and when Claude should use it.
Use when writing, reviewing, or debugging Terraform/OpenTofu modules, tests, CI, scans, or state ops - diagnoses failure mode (identity churn, secrets, blast radius, CI drift, state corruption) with version-aware guards.
Pause for review every N tasks - selective autonomy pattern
Launch Loki Mode autonomous SDLC agent. Handles PRD-to-deployment with minimal human intervention. Invoke for multi-phase development tasks, bug fixing campaigns, or full product builds.
Applies prompt repetition to improve accuracy for non-reasoning LLMs
Autonomous spec-driven build system with a built-in trust layer. It does not call work done until it is verified (RARV-C closure loop, 8 quality gates, completion council, verified-completion evidence gate). Triggers on "Loki Mode". Takes a spec (PRD, GitHub…
Catalogue of known SDLC anti-patterns that great_cto agents must actively reject when reviewing architecture, plans, code, or post-mortems. Used by architect (pre-impl), pm (planning), senior-dev (impl), l3-support (post-incident).
Analyze images, websites, and Figma files to extract their design and generate a `design.md` with token system, component inventory, and reconstruction notes. Use this skill whenever the user wants to understand, document, replicate, or audit the design of…
Shared review framework that every domain reviewer (pci, oracle, gov, edtech, healthcare, mlops, etc.) MUST follow. Defines the output artifact (TM-{slug}.md), mandatory sections, severity scale, verdict format, the workflow scaffold (when-invoked, Step-0…
Structured idea generation + multi-LLM debate for the product-owner stage. Diverge (generate genuinely different bets), debate (a 4-persona panel on 4 models argues over 2 rounds), converge (synthesize a recommendation). Used by product-owner before…
Standardized cost-estimation framework for great_cto plans. Forces explicit LLM cost, infra cost, human-supervision time, and the (defensible) human-equivalent comparison. Output format is parsable by the board's /api/cost path — must follow exactly.
Distils repeating patterns from session logs and lessons.md into draft skill files. Run after ≥10 sessions to extract durable knowledge. Output: draft skills/ files + promotion report.
Spawns the decision-scorer agent after architect proposes 2+ variants in an ADR. Produces a weighted scoring table and recommended choice saved to docs/decisions/.
Structured pre-design questioning to surface hidden constraints before any architecture decision is locked in. Forces the architect/auditor/reviewer to enumerate what they DON'T know before proposing.
Reusable reporting contract for any agent that hands work back to the pipeline. Forces ONE of two terminal statuses (DONE or BLOCKED) with a specific evidence shape. Stops vague "probably finished" and "kind of stuck" verdicts.
Use when the CTO describes a feature, task, or project goal. Orchestrates the full SDLC pipeline automatically based on project type.
Email/SMS lifecycle and deliverability framework for SMB Product-Builder products that send transactional or lifecycle messages (booking reminders, CRM sequences, receipts, win-back). Codifies provider selection (Resend/Postmark/Twilio/SendGrid), domain auth…
Local-business SEO and structured-data framework for content-platform Product-Builder products that need to be found (storefronts, restaurant online-ordering, real-estate listings, service-business sites). Codifies schema.org structured data…
Data-model rules that make a schema importable from day one, so the migration-import-engineer is never blocked on missing columns. Every SMB Product-Builder product must let a customer bring their data from an incumbent (ServiceTitan/Toast/Mindbody/Shopify) —…
Scaffold-time observability so a shipped product is not blind in prod from day one — error capture (Sentry), request-id structured logging, and /healthz + /readyz endpoints. stack-baseline pins Sentry but nothing wires it; this is the wiring. Loaded by…
Build an Opportunity Solution Tree (OST) to structure product discovery — map a desired outcome to customer opportunities, possible solutions, and experiments. Based on Teresa Torres' Continuous Discovery Habits. Use when the team is unclear what to build…
Transform an output-focused roadmap (feature list) into an outcome-focused one. Rewrites initiatives as outcome statements reflecting user and business impact. Use when a roadmap lists features instead of results, when making a roadmap more strategic, or when…
Decomposition methodology for pm agent — turns an approved ARCH document into a Beads task list with explicit dependencies, time-boxes, and acceptance criteria. The pipeline can only orchestrate work it can see; this skill defines what "seeable work" looks…
Imagine the project has already shipped and failed catastrophically — work backwards from the failure to identify the most likely causes BEFORE building. Forces concrete risk identification, not vague "what could go wrong" lists.
Reusable writing-style contract for agent outputs (reports, ARCH docs, verdicts, threat models). Forces direct prose with concrete evidence, no marketing voice, no hedge words. The single most-referenced skill across the pipeline — used by 28 agents.
Reusable 3-round self-challenge + arbiter pattern for filtering false positives from findings/verdicts. Use when the cost of a false-positive gate block exceeds the cost of ~4 extra LLM turns.
The pinned default technology stack for SMB Product-Builder products. One source of truth so the architect, app-scaffolder, auth-engineer, and senior-dev never re-decide the stack per build — they build ON it. Covers framework, ORM/DB, auth, UI,…
Coverage-design method for qa-engineer — pyramid ratios per archetype, equivalence/boundary/property case selection, mutation score as the real coverage signal, and a flake-quarantine policy. Turns "coverage is 90%" (a number with no method) into a defensible…
UI/UX design intelligence for web and mobile. Includes 50+ styles, 161 color palettes, 57 font pairings, 161 product types, 99 UX guidelines, and 25 chart types across 10 stacks (React, Next.js, Vue, Svelte, SwiftUI, React Native, Flutter, Tailwind,…
Domain knowledge for the construction vertical (contractors, field crews) so architect and pm don't spec construction products naively. Covers the vocabulary (bid vs estimate, takeoff, retainage, change order, AIA G702/G703, lien waiver, draw schedule), the…
Domain-knowledge primer for the marketing & creator vertical (creators, newsletter writers, podcasters, course sellers) so architect/pm don't spec naively against incumbents (Substack ~10%, Patreon 8–12%, Kajabi $149+, beehiiv, Buffer/Hootsuite/Later).…
Domain-knowledge pack for fitness & wellness (boutique studios, gyms, coaches, on-demand brands) — the membership vocabulary, non-obvious billing/booking rules, and retention realities a builder must know so fitness products aren't speced naive. Covers the…
Domain-knowledge pack for home & field services (HVAC, plumbing, cleaning, landscaping) — the trades vocabulary, non-obvious pricing/dispatch rules, and field-crew realities a builder must know so home-services products aren't speced naive. Covers the four…
Domain-knowledge primer for the HR & recruiting vertical (ATS, onboarding, workforce scheduling, engagement). Applied by architect/pm during spec authoring so they aren't naive about hiring pipelines, the admitted offer→onboard data-carry gap, EEO/I-9…