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Scaffolding academic research projects and refactoring existing ones for Alex-assisted workflows
tier
extended
applyTo
**/*research*,**/*academic*,**/*scaffold*
Research Project Scaffold Skill
Scaffolding new academic research projects and refactoring existing ones for Alex-assisted workflows.
Purpose
Provide standardized structures and refactoring procedures for academic research projects that maximize Alex's ability to assist throughout the research lifecycle.
# [Project Title] - Research Context## Project Overview
[2-3 sentence summary of research focus and goals]
## Current Phase- [x] Literature Review
- [ ] Data Collection
- [ ] Analysis
- [ ] Writing
## Key Files- Research plan: docs/RESEARCH-PLAN.md
- Literature: references/LITERATURE-MATRIX.md
- Methodology: docs/METHODOLOGY.md
## Alex Guidance- When reviewing literature: Add entries to LITERATURE-MATRIX.md
- When analyzing data: Document steps in DECISION-LOG.md
- When writing: Check references against LITERATURE-MATRIX.md
- Citation style: [APA 7 / Chicago / IEEE / etc.]
## Domain Context
[Key concepts, terminology, or background Alex needs]
## Quality Standards- All claims require citations or data references
- Methodology decisions logged with rationale
- Raw data never modified (work from processed/)
Refactoring Existing Projects
Assessment Checklist
Run this audit on any existing research project:
## Research Project Audit### Structure Assessment- [ ] Has dedicated .github/ folder with copilot-instructions.md
- [ ] Data separated: raw vs processed
- [ ] Clear separation: analysis code vs writing
- [ ] References organized and tracked
### Documentation Assessment - [ ] Research questions documented
- [ ] Methodology decisions recorded
- [ ] Literature systematically tracked (not scattered notes)
- [ ] Decision rationale captured
### Alex-Readiness Assessment- [ ] Context file exists (copilot-instructions.md or equivalent)
- [ ] Current phase clearly marked
- [ ] Key terminology defined
- [ ] Citation style specified
### Data Management Assessment- [ ] Raw data preserved unchanged
- [ ] Data dictionary exists
- [ ] Analysis reproducible
- [ ] Sensitive data protected
### Inclusion Criteria1. Age โฅ [minimum] years
2. [Clinical condition or symptom]
3. [Baseline test values] (e.g., eGFR > 60)
4. Ability to provide informed consent
5. Willing to comply with study procedures
### Exclusion Criteria1.**Organ impairment**: [specific threshold]
2.**Current medication use**: [contraindicated drugs]
3.**Comorbid conditions**: [list with rationale]
4.**Concurrent medications** due to interaction risk:
- [Drug class 1] (rationale)
- [Drug class 2] (rationale)
5.**Pregnancy or planning pregnancy**6.**Life expectancy < [study duration]**
External IRB Selection (Non-Academic Settings)
IRB
Cost Range
Timeline
Best For
Sterling IRB
$1,500-3,000
2-3 weeks
Supplement studies
Solutions IRB
$1,000-2,500
2-3 weeks
Budget-conscious
Advarra
$2,000-4,000
2-4 weeks
Academic spinoffs
WCG IRB
$2,500-5,000
2-4 weeks
Large commercial
Budget: Add $2,000-3,000 for IRB fees + 4-6 weeks to timeline.
Evidence Confidence Levels
Level
Meaning
Basis
HIGH
Strong consensus
Multiple RCTs, mechanisms confirmed
MODERATE
Promising
Animal studies, small human trials
LOW
Emerging
Case reports, theoretical basis only
INSUFFICIENT
Unknown
No quality evidence available
Stakeholder Materials
README.md โ 3-minute pitch for decision-makers
EXECUTIVE-SUMMARY.md โ 1-page BLUF for busy executives