dosage-calc

name	dosage-calc
description	Calculate drug dosages with renal and hepatic adjustments. Use standard references only. Not for direct patient care.

Dosage Calculation

⚠️ For research and clinical reference only. Do not use for direct patient care without verification.

References

• FDA label (Drugs@FDA)
• EMA EPAR
• Lexicomp / UpToDate
• Manufacturer prescribing information

Adjustments

Organ Function	Adjustment Method
Renal (CrCl <30)	Dose reduction or interval extension
Renal (CrCl 30-50)	Moderate adjustment
Hepatic (Child-Pugh B)	Usually 50% reduction
Hepatic (Child-Pugh C)	Avoid or significant reduction

Formulas

• BSA: DuBois formula
• CrCl: Cockcroft-Gault
• eGFR: CKD-EPI

Output

Save calculation to outputs/dosage-<slug>.md with all formulas and references cited.