| name | KSB-D02-K0007 |
| description | Pharmacokinetic Factors: Absorption, distribution, metabolism, excretion variations... |
| version | 1.0.0 |
| domain | D02 |
| domain_name | Clinical Aspects of ADRs |
| type | Knowledge |
| proficiency_level | L3 |
| bloom_level | analyze |
| triggers | ["explain pharmacokinetic factors","what is pharmacokinetic factors","analyze pharmacokinetic factors"] |
| epa_mapping | EPA-01, EPA-02, EPA-05 |
| cpa_mapping | CPA-01, CPA-02 |
| regulatory_refs | ICH-E2A, FDA-GUID-001 |
KSB-D02-K0007: Pharmacokinetic Factors
Overview
Domain: D02 - Clinical Aspects of ADRs
Type: Knowledge
Proficiency Level: L3 (Competent - Minimal supervision)
Bloom Level: Analyze
Description
Absorption, distribution, metabolism, excretion variations
Context
- Major Section: ADR Classification Systems
- Section: Pharmacological Mechanisms
EPA Mapping
- EPA-01:3001-3003
- EPA-02:3004-3005
- EPA-05:3011-3012
CPA Pathway
Regulatory References
Instructions
When this skill is activated, Claude should:
- Demonstrate L3 proficiency in pharmacokinetic factors
- Apply analyze level cognitive skills to analyze the topic
- Reference relevant regulatory guidance (ICH-E2A, FDA-GUID-001)
- Connect to related EPAs: EPA-01, EPA-02, EPA-05
Key Competencies
- Absorption, distribution, metabolism, excretion variations
Assessment Criteria
- Can analyze core concepts independently
- Demonstrates understanding of regulatory context
- Applies knowledge appropriately to PV scenarios
Related Skills
- Other D02 skills in Pharmacological Mechanisms
- Cross-domain integrations per DAG architecture
Generated from PV KSB Framework v1.0 | 2025-12-31
