target-assessment

name	Target Assessment
description	Assess a biological target's druggability and risk into a go / no-go recommendation.
category	Research

Target Assessment

Judge whether a target is worth a program — how druggable it is, and what could kill it — before resources go in.

When to use

• A target is proposed and needs a rigorous read before committing.
• Two targets compete for the same program slot.

Steps

1. Establish the biological rationale linking target to disease.
2. Assess druggability — structure, binding sites, and modality fit.
3. Scan the competitive and IP landscape around the target.
4. Surface the risks: safety liabilities and validation gaps.
5. Weigh it into a go / no-go with the reasoning.

Output

A target assessment: rationale, druggability, landscape, risks, and a go / no-go, following the [[Research standards]]. The operator decides to commit.