cbioportal-search

name	cbioportal-search
description	Resolve cancer genes and plan public cBioPortal cohort queries. Use for somatic alteration, cancer cohort, co-alteration, survival, or translational oncology evidence.
license	MIT

cBioPortal Search

1. Resolve the canonical gene with science_search_cbioportal and cross-check Entrez/Ensembl IDs.
2. Define cancer type, study, molecular profile, sample list, alteration class, and denominator before cohort retrieval.
3. Preserve study version, sample/patient unit, assay platform, filtering, missingness, alteration frequency, and access time.
4. Use $cx-cancer-genomics-evidence for multi-cohort synthesis and $science-review before translational conclusions.

Do not compare frequencies across cohorts without reconciling eligibility, assay coverage, sample unit, and missing data. This is not patient-specific interpretation.

Store cohort queries and denominators with $science-provenance before $science-review.

Source basis: cBioPortal web API.