kdense-pathway-enrichment

Run pathway and gene-set enrichment analysis on gene lists or ranked gene data, then interpret the results. Use whenever the user has a set of genes (differentially expressed genes from PyDESeq2/Scanpy, CRISPR-screen hits, cluster marker genes, proteomics hits) and wants to know which biological pathways, GO terms, or gene sets are over-represented or enriched. Covers over-representation analysis (ORA / Enrichr / Fisher / hypergeometric), ranked Gene Set Enrichment Analysis (GSEA / preranked), single-sample scoring (ssGSEA/GSVA), and functional profiling via gseapy, g:Profiler, Enrichr libraries, MSigDB, GO, KEGG, Reactome, and WikiPathways — plus gene-ID mapping, choosing the right background universe, multiple-testing correction, redundancy reduction, dotplots/enrichment maps, and publication-ready tables. Use this for "pathway analysis", "enrichment analysis", "GO enrichment", "KEGG/Reactome pathways", "GSEA", "over-representation", "functional annotation", or "what pathways are my genes in".

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Dépôt: eightmm/codex-science
Dernière activité de la source: 10 juillet 2026 à 05:18
Langue détectée de SKILL.md: anglais
Étoiles: 2
Forks: 0

Options d'installation

Le prompt qui vérifie d'abord la source est sélectionné par défaut. Vous pouvez passer à une commande directe ou télécharger une copie locale.

Installer avec Codex ou Claude Copiez ce prompt, collez-le dans Codex, Claude ou un autre assistant, puis laissez-le vérifier la page du skill et l'installer pour vous.

Une commande directe contourne le prompt de vérification. Examinez la source avant de l'exécuter.

npx skills add https://github.com/eightmm/codex-science --skill kdense-pathway-enrichment

La commande reste sur une seule ligne. Faites défiler horizontalement pour la vérifier avant de la copier.

Vous préférez une copie locale ? Téléchargez les fichiers actuellement disponibles dans SkillsMP.

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SKILL.md

Instructions source · Aperçu en lecture seule

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Kdense Pathway Enrichment

Use this Codex adapter for the pinned upstream scientific skill.

Catalog status

Status: inactive

Source: kdense

Audit reasons: executable-content

Upstream license: MIT

Inventory: ../../inventory.json

Upstream instructions: ../../../vendor/scientific-agent-skills/skills/pathway-enrichment/SKILL.md

Procedure

Resolve the plugin root as three directories above this skill directory.

Read the matching inventory record and verify its status, reasons, source path, and pinned revision.

Do not read the upstream instructions until the user has seen every audit reason and given explicit acknowledgement. Acknowledgement permits instruction inspection only.

Treat upstream frontmatter as source metadata, not as Codex configuration. Follow the instruction body only where it is compatible with available Codex tools and the current user-approved plan.

Treat tools named for another agent runtime as capability requests. Map them to an available Codex tool only when the behavior is equivalent; otherwise report the unavailable capability.

Ask before credentials, package installation, new network hosts, remote compute, writes, paid services, destructive actions, or imported executable code.

Use $science-provenance for produced scientific outputs and $science-review before presenting scientific claims.

Boundaries

This wrapper does not grant credentials, network access, package installation, or script execution.

Do not change an inactive record to active from inside a research task.

Preserve failures, uncertainty, source identifiers, and licensing constraints.