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Calculate KDIGO AKI (Acute Kidney Injury) staging for ICU patients using creatinine and urine output criteria. Use for nephrology research, AKI outcome studies, or renal function monitoring.
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| name | kdigo-aki-staging |
| description | Calculate KDIGO AKI (Acute Kidney Injury) staging for ICU patients using creatinine and urine output criteria. Use for nephrology research, AKI outcome studies, or renal function monitoring. |
| tier | validated |
| category | clinical |
The Kidney Disease: Improving Global Outcomes (KDIGO) criteria define Acute Kidney Injury (AKI) stages based on serum creatinine changes and/or urine output reduction.
In M4Bench, target concept tables listed in the task configuration are removed or unavailable in the agent database. Use this skill as procedural guidance and derive the requested output from available source or intermediate tables; do not rely on a precomputed target table or bundled SQL script.
| Stage | Creatinine Criterion |
|---|---|
| 1 | >= 1.5x baseline within 7 days OR >= 0.3 mg/dL increase within 48h |
| 2 | >= 2.0x baseline |
| 3 | >= 3.0x baseline OR >= 4.0 mg/dL with acute increase OR RRT initiation |
| Stage | Urine Output Criterion |
|---|---|
| 1 | < 0.5 mL/kg/h for 6-12 hours |
| 2 | < 0.5 mL/kg/h for >= 12 hours |
| 3 | < 0.3 mL/kg/h for >= 24 hours OR anuria for >= 12 hours |
Final AKI Stage = MAX(creatinine stage, urine output stage, CRRT stage)
Baseline Creatinine: Uses the lowest creatinine in the past 7 days as the baseline. This may underestimate AKI if patient was already in AKI on admission.
48-Hour Window: The >= 0.3 mg/dL acute increase criterion uses the lowest creatinine in the past 48 hours specifically.
Stage 3 with Cr >= 4.0: Requires EITHER:
Urine Output Timing: UO criteria require the patient to be in ICU for at least 6 hours before staging (KDIGO definition). Earlier times get stage 0.
Weight for UO Calculation: Use documented or estimated patient weight from available charted weight records. Weight estimation methods vary.
CRRT as Stage 3: Any patient on CRRT is automatically Stage 3 AKI.
Smoothed Stage: aki_stage_smoothed carries forward the maximum stage from the past 6 hours to reduce fluctuation between creatinine/UO measurements.
Time Series Data: AKI is calculated at every creatinine/UO measurement time, not just once per admission.
