nccn-colon-cancer

name	nccn-colon-cancer
description	NCCN clinical practice guideline navigation for Colon Cancer. Use when a clinician needs treatment decisions, staging, workup, or evidence for Colon Cancer based on NCCN Guidelines version 2.2026.
metadata	{"author":"nccn-skill-generator","version":"2.2026","source":"NCCN Clinical Practice Guidelines in Oncology","guideline":"Colon Cancer"}
license	See NCCN terms of use

NCCN Guidelines: Colon Cancer

Clinical decision support derived from NCCN Clinical Practice Guidelines in Oncology. Version 2.2026.

Disease Subtypes

pMMR/MSS: Findings, Primary Treatment Colon Cancer Appropriate for Resection

• Evidence: pMMR/MSS: Findings, Primary Treatment Colon Cancer Appropriate for Resection -- Discussion of clinical evidence and rationale

pMMR/MSS: Treatment for Resectable synchronous liver and/or lung mets only

• Algorithm: pMMR/MSS: Treatment for Resectable synchronous liver and/or lung mets only -- Staging, workup, and treatment pathways
• Evidence: pMMR/MSS: Treatment for Resectable synchronous liver and/or lung mets only -- Discussion of clinical evidence and rationale

Surveillance

• Evidence: Surveillance -- Discussion of clinical evidence and rationale

Recurrence and Workup

• Algorithm: Recurrence and Workup -- Staging, workup, and treatment pathways

pMMR/MSS: Unresectable Metachronous Metastases

• Evidence: pMMR/MSS: Unresectable Metachronous Metastases -- Discussion of clinical evidence and rationale

dMMR/MSI-H or POLE/POLD1: Suspected or Proven Metastatic Synchronous Adenocarcinoma

• Evidence: dMMR/MSI-H or POLE/POLD1: Suspected or Proven Metastatic Synchronous Adenocarcinoma -- Discussion of clinical evidence and rationale

dMMR/MSI-H or POLE/POLD1: Resectable Metachronous Metastases

• Algorithm: dMMR/MSI-H or POLE/POLD1: Resectable Metachronous Metastases -- Staging, workup, and treatment pathways

Literature Search Criteria

• Evidence: Literature Search Criteria -- Discussion of clinical evidence and rationale

Risk Assessment

• Evidence: Risk Assessment -- Discussion of clinical evidence and rationale

Appendiceal Neoplasms

• Evidence: Appendiceal Neoplasms -- Discussion of clinical evidence and rationale

Clinical Presentation and Treatment of Nonmetastatic Disease

• Evidence: Clinical Presentation and Treatment of Nonmetastatic Disease -- Discussion of clinical evidence and rationale

Management of Metastatic Disease

• Evidence: Management of Metastatic Disease -- Discussion of clinical evidence and rationale

Endpoints for Advanced CRC Clinical Trials

• Evidence: Endpoints for Advanced CRC Clinical Trials -- Discussion of clinical evidence and rationale

Post-Treatment Surveillance

• Evidence: Post-Treatment Surveillance -- Discussion of clinical evidence and rationale

Summary

• Evidence: Summary -- Discussion of clinical evidence and rationale

References

Shared Resources

Principles of Imaging

• Principles of Imaging -- Imaging and surveillance guidelines

Principles of Pathologic and Molecular Review

• Principles of Pathologic and Molecular Review -- General treatment principles

Principles of Surgery and Locoregional Therapies

• Principles of Surgery and Locoregional Therapies -- General treatment principles

Systemic Therapy for Advanced or Metastatic Disease

• Systemic Therapy for Advanced or Metastatic Disease -- Shared clinical resource

Principles of Radiation and Chemoradiation Therapy

• Principles of Radiation and Chemoradiation Therapy -- Radiation therapy guidelines

Principles of Risk Assessment for Stage II Disease

• Principles of Risk Assessment for Stage II Disease -- General treatment principles

Principles of Adjuvant Therapy

• Principles of Adjuvant Therapy -- General treatment principles

Principles of Survivorship

• Principles of Survivorship -- Survivorship care guidelines

Principles of Appendiceal Adenocarcinoma

• Principles of Appendiceal Adenocarcinoma -- General treatment principles

Principles of Pharmacogenetics

• Principles of Pharmacogenetics -- General treatment principles

Staging

• Staging -- Staging classification

Overview

• Overview (Evidence) -- Shared clinical resource

Guidelines Update Methodology

• Guidelines Update Methodology (Evidence) -- Shared clinical resource

Sensitive/Inclusive Language Usage

• Sensitive/Inclusive Language Usage (Evidence) -- Shared clinical resource

Staging

• Staging -- Staging classification

Pathology

• Pathology (Evidence) -- Pathologic evaluation guidelines

Survivorship

• Survivorship -- Survivorship care guidelines

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Citation: NCCN Clinical Practice Guidelines in Oncology: Colon Cancer, Version 2.2026. National Comprehensive Cancer Network. Available at nccn.org.

This skill references copyrighted NCCN content. Refer to nccn.org for the authoritative source and full terms of use.