setup-env

name	setup-env
version	2.0.1
description	Creates isolated Python environments with uv (uv sync, uv run, PEP 723 scripts) from pyproject.toml or requirements.txt. Use when bootstrapping a Python repo so dependencies stay locked and isolated. Not for Node/npm, Vercel env var management (env-vars), or falling back to system pip when uv is missing.
risk	safe
source	openrouter-deepsearch
date_added	2026-06-16T00:00:00.000Z

Skill: Manage Python environments with uv

uv is a single, fast tool that replaces the python -m venv + pip + pip-tools stack. This skill tells the agent how to pick the right uv workflow for a given repository, create an isolated environment, install dependencies reproducibly, and run the project's code. The goal is that the agent never has to "remember" which shell the venv was activated in or whether the lockfile is current — uv resolves both for us on every run.

All commands below were checked against uv 0.11.19 (released 2026-06-03). If the installed uv is older and a flag is rejected, run uv <command> --help to see what that version supports rather than guessing.

When to Use

• The repository is a Python project. uv is Python-specific and has no value for other ecosystems.
• You need an isolated environment so the project's dependencies do not collide with the system interpreter or with another project's pins.
• You need reproducibility: a uv.lock lets the same versions resolve on every machine and in CI, which is the main reason to prefer uv sync over ad-hoc installs.
• You are running a single-file script that declares its own dependencies inline (PEP 723). uv run builds a throwaway environment for it automatically.

Trigger keywords: Python project, virtual environment, venv, dependencies, uv, pyproject.toml, requirements.txt, uv.lock, PEP 723, uv sync, uv run, uv pip install.

When NOT to use

• Non-Python projects — there is nothing for uv to manage.
• uv is not on PATH. Detect this first (uv --version); if it fails, stop and ask the user to install it rather than falling back to system pip, which would defeat the isolation this skill exists to provide.
• The repo has no pyproject.toml, no requirements.txt, and no PEP 723 markers. There is nothing to resolve, so report that instead of inventing a configuration.
• A legacy setup.py-only project that cannot be installed in editable mode. uv can often still build it, but if the build back-end is unusual, prefer the project's documented setup steps over forcing a uv workflow.

Prerequisites

1. uv must be installed and on PATH. Verify before doing anything else:

   uv --version
   

   If this fails, stop and ask the user to install uv from https://docs.astral.sh/uv/. Do not fall back to system pip.
2. Windows host is primary (PowerShell). All commands are tested in PowerShell 5.1+ on Windows. Where Linux/macOS paths differ, they are noted inline.
3. The repository must contain at least one of: pyproject.toml, requirements.txt, or a .py file with a PEP 723 # /// script block.

Procedure

Step 0 — Detect uv and confirm version

uv --version

Expected output (or newer):

uv 0.11.19

If the command is not found, stop. Do not proceed with system pip.

Step 1 — Select the workflow (decision order)

Detect the configuration in this order and use the first match. The order matters: a pyproject.toml is the most declarative source of truth, so it wins over a requirements.txt that may only list a subset of dependencies.

Priority	File present	Workflow	Key commands
1	pyproject.toml	Project workflow	uv sync, uv run
2	requirements.txt	Pip workflow	uv venv, uv pip install -r
3	.py with PEP 723 block	Inline workflow	uv run script.py
4	None of the above	Stop	Report: No supported dependency configuration found

---

Step 2A — Project workflow (pyproject.toml)

Run from the directory that contains pyproject.toml.

Create the environment and install dependencies

# If a lockfile already exists, install exactly what it pins and fail on drift.
uv sync --locked

# First run, or when you intend to (re)resolve and write uv.lock:
uv sync

Why two forms: uv sync --locked asserts that uv.lock is already up to date with pyproject.toml and errors if it is not — ideal in CI and when you must not change versions. Plain uv sync resolves dependencies and creates/updates uv.lock, which is what you want the first time or after editing dependencies. uv creates the environment at .venv in the project root (the standard location every editor and tool already understands); it is not a custom path.

Run scripts, modules, and tools

Always go through uv run so the environment is synced before the command executes:

uv run -- python main.py --config config/prod.toml
uv run -- python -m app.cli serve --port 8000
uv run -- pytest -q

The -- separates uv's own flags from the command's flags, so a --port meant for your app is never mistaken for a uv option.

For reproducible runs that must not trigger a re-resolve, add --frozen (use the existing lockfile and environment as-is):

uv run --frozen -- pytest -q

---

Step 2B — Pip workflow (requirements.txt)

Use this when the project only ships a requirements.txt (common in older repos and some deployment setups). It mirrors a classic pip flow but keeps the speed and isolation of uv.

Create the virtual environment

uv venv          # creates .venv in the current directory

By default this environment is minimal and does not include pip/setuptools. That is fine because uv pip install does the installing. Only add --seed if some downstream tool shells out to pip or setuptools inside the venv and therefore needs them present:

uv venv --seed   # also installs pip, setuptools, and wheel into .venv

Install dependencies

uv pip install targets the .venv it just found in the project, so create the venv first, then install into it:

uv pip install -r requirements.txt

uv's default resolution already prefers the highest compatible versions. Pass --resolution only when you deliberately want different behavior — for example, --resolution=lowest-direct to test against the minimum versions your project claims to support:

uv pip install --resolution=lowest-direct -r requirements.txt

Run scripts and modules

Prefer uv run, which still works without a pyproject.toml and uses the project's .venv:

uv run -- python main.py
uv run -- python -m app.cli --help

If you must call the interpreter directly (for example in a container entrypoint), use the path for the current OS. This is why uv run is preferred — it removes the need to branch on platform:

# Windows (PowerShell or cmd) — primary host
.venv\Scripts\python.exe main.py

# Linux / macOS
.venv/bin/python main.py

---

Step 2C — Inline workflow (PEP 723 single-file scripts)

A PEP 723 script declares its own dependencies in a comment block, so it needs no pyproject.toml and no pre-created venv. uv run reads the block, builds an ephemeral environment, and executes the file — ideal for one-off tools and reproducible single-file utilities.

uv run analysis/fetch_status.py https://example.com --timeout 5

# Force "treat this path as a script" mode if uv's auto-detection is ambiguous:
uv run --script analysis/fetch_status.py https://example.com

Example PEP 723 script (modern, fully typed, defensive)

This is a complete, runnable example. It demonstrates the standard every script this skill produces should meet: explicit type annotations on all parameters and returns, strict validation of inputs before use, defensive error handling around I/O, and no Any types or bare except. Save it as analysis/fetch_status.py and run it with the command above.

# /// script
# requires-python = ">=3.10"
# dependencies = [
#   "httpx>=0.27",
# ]
# ///
"""Fetch a URL and print its HTTP status, with strict validation and error handling."""

from __future__ import annotations

import argparse
import sys
from dataclasses import dataclass

import httpx


@dataclass(frozen=True)
class Arguments:
    """Validated command-line arguments."""

    url: str
    timeout: float


def parse_arguments(argv: list[str]) -> Arguments:
    """Parse and validate argv, exiting with a clear message on invalid input."""
    parser = argparse.ArgumentParser(
        description="Fetch a URL and print its HTTP status code.",
    )
    parser.add_argument("url", type=str, help="Absolute http:// or https:// URL.")
    parser.add_argument(
        "--timeout",
        type=float,
        default=10.0,
        help="Request timeout in seconds (must be greater than 0).",
    )
    namespace = parser.parse_args(argv)

    url: str = namespace.url
    timeout: float = namespace.timeout

    # Validate at the boundary so the rest of the program can trust its inputs.
      url.startswith((, )):
        parser.error()
     timeout <= :
        parser.error()

     Arguments(url=url, timeout=timeout)


 () -> :
    
    :
        response = httpx.get(url, timeout=timeout, follow_redirects=)
     httpx.HTTPError  exc:
        (, file=sys.stderr)
         

    ()
     


 () -> :
    
    args = parse_arguments(sys.argv[:]  argv    argv)
     fetch_status(args.url, args.timeout)


 __name__ == :
     SystemExit(main())

---

Step 3 — Bootstrap an unknown repo end to end

When the agent needs to set up an unknown repo end to end, use one of the scripts below. Both fail fast with a clear message if uv is missing and pick the workflow from the files actually present, so they are safe to run unattended.

PowerShell (Windows — primary host)

#Requires -Version 5.1
$ErrorActionPreference = 'Stop'

if (-not (Get-Command uv -ErrorAction SilentlyContinue)) {
    Write-Error 'uv is not on PATH. Install it from https://docs.astral.sh/uv/ and retry.'
    exit 127
}

Write-Host "Using $(uv --version)"

if (Test-Path 'pyproject.toml') {
    Write-Host 'Detected pyproject.toml -> project workflow'
    if (Test-Path 'uv.lock') { uv sync --locked } else { uv sync }
}
elseif (Test-Path 'requirements.txt') {
    Write-Host 'Detected requirements.txt -> pip workflow'
    uv venv
    uv pip install -r requirements.txt
}
else {
    Write-Error 'No pyproject.toml or requirements.txt found. For a PEP 723 script run: uv run path\to\script.py'
    exit 1
}

Write-Host 'Environment ready.'

Bash (Linux / macOS)

#!/usr/bin/env bash
# Bootstrap a Python project's environment with uv, choosing the right workflow.
set -euo pipefail

# Fail fast and explain how to recover if uv is unavailable.
if ! command -v uv >/dev/null 2>&1; then
  echo "error: uv is not on PATH. Install it from https://docs.astral.sh/uv/ and retry." >&2
  exit 127
fi

echo "Using $(uv --version)"

if [[ -f pyproject.toml ]]; then
  echo "Detected pyproject.toml -> project workflow"
  if [[ -f uv.lock ]]; then
    uv sync --locked          # reproducible: error if the lockfile is stale
  else
    uv sync                   # first run: resolve and write uv.lock
  fi
elif [[ -f requirements.txt ]]; then
  echo "Detected requirements.txt -> pip workflow"
  uv venv                     # creates .venv in the project root
  uv pip install -r requirements.txt
else
  echo "error: no pyproject.toml or requirements.txt found." >&2
  echo "For a single-file PEP 723 script, run it directly: uv run path/to/script.py" >&2
  exit 1
fi

echo "Environment ready."

Pitfalls

1. uv not on PATH. Always check uv --version first. If it fails, stop and ask the user to install it. Never fall back to system pip — that defeats the isolation this skill exists to provide.
2. Manual venv activation is stateful and shell-specific. It is the usual source of "works in my terminal, fails in the agent's." Always prefer uv run over .\.venv\Scripts\Activate.ps1 or source .venv/bin/activate. uv run re-syncs the project environment and executes the command inside it every time, with no activation step.
3. uv sync --locked vs plain uv sync confusion. --locked errors if uv.lock is stale relative to pyproject.toml — use it in CI or when you must not change versions. Plain uv sync resolves and writes uv.lock — use it on first run or after editing dependencies. Using --locked on a first run (no lockfile) will fail.
4. Missing -- separator. Without --, a flag like --port meant for your app can be mistaken for a uv option. Always use uv run -- <command>.
5. uv venv without --seed breaks downstream tools that shell out to pip. The default venv is minimal (no pip/setuptools). Only add --seed if a downstream tool requires pip or setuptools inside the venv.
6. Windows path separators. On Windows, use backslashes: .venv\Scripts\python.exe. On Linux/macOS, use forward slashes: .venv/bin/python. uv run avoids this branching entirely.
7. No supported configuration found. If the repo has no pyproject.toml, no requirements.txt, and no PEP 723 markers, do not invent a configuration. Report: No supported dependency configuration found (expected pyproject.toml, requirements.txt, or a PEP 723 script).
8. Legacy setup.py-only projects. can often still build these, but if the build back-end is unusual, prefer the project's documented setup steps over forcing a workflow.

Verification

Confirm the environment is healthy before declaring the setup complete. Each check below maps to a real uv 0.11.x command:

1. uv is installed and recent:

   uv --version
   

   Expected: prints a version string (e.g., uv 0.11.19 or newer).

2. The chosen configuration file exists — i.e., the workflow selection was correct:

   Test-Path pyproject.toml    # or requirements.txt, or PEP 723 block in .py
   

3. Tests pass (skip if the project has no tests, and say so):

   uv run -- pytest -q
   

4. Expected packages are installed:

   uv pip list
   

5. No broken or incompatible dependencies:

   uv pip check
   

   Expected: No issues found or equivalent clean output.

6. Resolved dependency graph has no unexpected conflicts:

   uv tree
   

7. Review outdated packages (informational — outdated is not a failure):

   uv pip list --outdated
   

Related skills

• Python project setup and packaging (pyproject.toml, build back-ends).
• Reproducible dependency management with uv.lock (uv sync --locked / --frozen).
• Writing PEP 723 self-contained scripts.
• CI configuration for Python (cache .venv / uv cache, run uv sync --locked).