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Open Targets gene-disease association lookup via the official MCP connector. One GraphQL round trip per gene. Emits Tier C informational evidence.
Codex または Claude でインストール この Prompt をコピーして Codex、Claude、または他のアシスタントに貼り付けると、Skill ページを確認してインストールできます。
SOC 職業分類に基づく
Standing watcher. Reruns the trial, literature (PubMed + bioRxiv), and ClinVar-relookup specialists against the FIXED profile and diffs against the stored baseline. Empty diff -> one calm "no significant changes" timeline entry.
PubMed + bioRxiv search for recent literature on the patient's genes and diagnosis. bioRxiv preprints are first-class (earliest signal). Emits Tier C; the LLM only summarizes genuine free text, it never asserts facts.
ClinicalTrials.gov v2 search for trials relevant to the patient's diagnosis and genes. Eligibility is surfaced as "may be eligible — confirm with your care team", never confirmed. Emits Tier C.
Uncertainty-ranked gap report (spec §8b). For an unresolved (Tier B) variant, names that the analysis can't resolve it and attributes the gap to a missing input — a documented family history — that would let the analysis weight it. Never a test order.
Uncertainty-ranked gap report (spec §8b). Names a pharmacogenomic module the analysis could NOT complete and attributes the gap to a specific missing input (a genotype). Never tells the patient to get a test — it is a report on the tool's blind spots for the care team.
Deterministic CPIC pharmacogenomics lookup over the patient's current medications. Pure code, no LLM. Emits Tier A/B for CPIC Level A/B gene-drug pairs; flags a missing genotype instead of ever directing a dose change.
| name | target-open-targets |
| kind | oneshot |
| domain | target |
| description | Open Targets gene-disease association lookup via the official MCP connector. One GraphQL round trip per gene. Emits Tier C informational evidence. |
For each gene on the profile, query Open Targets (official MCP connector, one
GraphQL round trip) for gene-disease associations relevant to the existing
diagnosis. Emits Tier C informational EvidenceRecords: association score,
the disease, and a resolvable Open Targets URL as source_url.
Framing rules (spec §2): report associations as literature/association facts ("associated with ... in Open Targets"), never as anything the patient "has".
STATUS: stub. The MCP call is not wired yet; run_specialist returns [] so the
coordinator runs cleanly end-to-end. Wire the Open Targets MCP connector, map each
association to an EvidenceRecord(domain="target", tier="C", ...), and verify the
source_url is well-formed before emitting.
