stress-test-feasibility

name	stress-test-feasibility
description	Stress-test eligibility criteria against the addressable population and site capacity before the protocol locks, since restrictive criteria are the biggest enrollment killer. Reach for this at design.

Skill: Stress-test protocol feasibility

Two-thirds of sites miss enrollment; feasibility is set at design.

Step 1 — Map eligibility to population

Estimate the enrollable pool after each inclusion/exclusion criterion (§3 #1).

Step 2 — Find the criteria that shrink the pool

Flag the high-cost criteria and whether they're scientifically necessary.

Step 3 — Check site capacity

Match the pool to realistic site enrollment rates.

Step 4 — Recommend, as decision-support

Propose criteria adjustments for the medical team to weigh.

Output

An eligibility-vs-population read, the pool-shrinking criteria, a site-capacity check, and decision-support recommendations.