ComeOnOliver/skillshub - 第 21 页

recombinator

Produce offspring genomes from parent pairs via meiotic recombination, mutation, and clinical evaluation

原文语言：英语

repro-enforcer

Export any bioinformatics analysis as a reproducible bundle with Conda environment, Singularity container definition, and Nextflow pipeline.

原文语言：英语

rnaseq-de

Differential expression analysis for bulk RNA-seq and pseudo-bulk count matrices with QC, PCA, and contrast testing.

原文语言：英语

scrna-embedding

Local scVI-based single-cell latent embedding and batch-aware integration from raw-count .h5ad or 10x Matrix Market input, with stable integrated AnnData export for downstream latent analysis.

原文语言：英语

scrna-orchestrator

Local Scanpy pipeline for single-cell RNA-seq QC, optional doublet detection, clustering, marker discovery, optional CellTypist annotation, optional latent downstream mode from integrated.h5ad/X_scvi, and optional two-group contrastive marker analysis from…

原文语言：英语

seq-wrangler

Sequence QC, alignment, and BAM processing. Wraps FastQC, BWA/Bowtie2, SAMtools for automated read-to-BAM pipelines.

原文语言：英语

soul2dna

Compile SOUL.md character profiles into synthetic diploid genomes (.genome.json) via trait-to-allele mapping

原文语言：英语

struct-predictor

Local protein structure prediction with AlphaFold, Boltz, or Chai. Compare predicted structures, compute RMSD, visualise 3D models.

原文语言：英语

target-validation-scorer

Evidence-grounded target validation scoring with GO/NO-GO decisions for drug discovery campaigns

原文语言：英语

ukb-navigator

Semantic search across UK Biobank's 12,000+ data fields and publications — find the right variables for your research question.

原文语言：英语

variant-annotation

Annotate VCF variants with Ensembl VEP REST, ClinVar significance, gnomAD/population frequency context, and prioritized variant ranking.

原文语言：英语

vcf-annotator

Annotate VCF variants with VEP, ClinVar, gnomAD frequencies, and ancestry-aware context. Generates prioritised variant reports.

原文语言：英语

clickhouse-best-practices

MUST USE when reviewing ClickHouse schemas, queries, or configurations. Contains 28 rules that MUST be checked before providing recommendations. Always read relevant rule files and cite specific rules in responses.

原文语言：英语

analyzing-projects

Analyzes codebases to understand structure, tech stack, patterns, and conventions. Use when onboarding to a new project, exploring unfamiliar code, or when asked "how does this work?" or "what's the architecture?"

原文语言：英语

convex-backend

Convex backend development guidelines. Use when writing Convex functions, schemas, queries, mutations, actions, or any backend code in a Convex project. Triggers on tasks involving Convex database operations, real-time subscriptions, file storage, or…

原文语言：英语

database-design

Designs database schemas, indexing strategies, query optimization, and migration patterns for SQL and NoSQL databases. Use when designing tables, optimizing queries, fixing N+1 problems, planning migrations, or when asked about database performance,…

原文语言：英语

designing-apis

Designs REST and GraphQL APIs including endpoints, error handling, versioning, and documentation. Use when creating new APIs, designing endpoints, reviewing API contracts, or when asked about REST, GraphQL, or API patterns.

原文语言：英语

designing-architecture

Designs software architecture and selects appropriate patterns for projects. Use when designing systems, choosing architecture patterns, structuring projects, making technical decisions, or when asked about microservices, monoliths, or architectural…

原文语言：英语

designing-tests

Designs and implements testing strategies for any codebase. Use when adding tests, improving coverage, setting up testing infrastructure, debugging test failures, or when asked about unit tests, integration tests, or E2E testing.

原文语言：英语

devops-infrastructure

Guides Docker, CI/CD pipelines, deployment strategies, infrastructure as code, and observability setup. Use when writing Dockerfiles, configuring GitHub Actions, planning deployments, setting up monitoring, or when asked about containers, pipelines,…

原文语言：英语

error-handling

Implements error handling patterns, structured logging, retry strategies, circuit breakers, and graceful degradation. Use when designing error handling, setting up logging, implementing retries, adding error tracking, or when asked about error boundaries, log…

原文语言：英语

managing-git

Manages Git workflows including branching, commits, and pull requests. Use when working with Git, creating commits, opening PRs, managing branches, resolving conflicts, or when asked about version control best practices.

原文语言：英语

optimizing-performance

Analyzes and optimizes application performance across frontend, backend, and database layers. Use when diagnosing slowness, improving load times, optimizing queries, reducing bundle size, or when asked about performance issues.

原文语言：英语

parallel-execution

Patterns for parallel subagent execution using Task tool with run_in_background. Use when coordinating multiple independent tasks, spawning dynamic subagents, or implementing features that can be parallelized.

原文语言：英语

security-patterns

Implements authentication, authorization, encryption, secrets management, and security hardening patterns. Use when designing auth flows, managing secrets, configuring CORS, implementing rate limiting, or when asked about JWT, OAuth, password hashing, API…

原文语言：英语

vercel-react-best-practices

React and Next.js performance optimization guidelines from Vercel Engineering. This skill should be used when writing, reviewing, or refactoring React/Next.js code to ensure optimal performance patterns. Triggers on tasks involving React components, Next.js…

原文语言：英语

web-design-guidelines

Review UI code for Web Interface Guidelines compliance. Use when asked to "review my UI", "check accessibility", "audit design", "review UX", "check my site against best practices", or "web interface guidelines".

原文语言：英语

-21risk-automation

Automate 21risk tasks via Rube MCP (Composio). Always search tools first for current schemas.

原文语言：英语

-2chat-automation

Automate 2chat tasks via Rube MCP (Composio). Always search tools first for current schemas.

原文语言：英语

ably-automation

Automate Ably tasks via Rube MCP (Composio). Always search tools first for current schemas.

原文语言：英语

abstract-automation

Automate Abstract tasks via Rube MCP (Composio). Always search tools first for current schemas.

原文语言：英语

abuselpdb-automation

Automate Abuselpdb tasks via Rube MCP (Composio). Always search tools first for current schemas.

原文语言：英语

abyssale-automation

Automate Abyssale tasks via Rube MCP (Composio). Always search tools first for current schemas.

原文语言：英语

accelo-automation

Automate Accelo tasks via Rube MCP (Composio). Always search tools first for current schemas.

原文语言：英语

accredible-certificates-automation

Automate Accredible Certificates tasks via Rube MCP (Composio). Always search tools first for current schemas.

原文语言：英语

acculynx-automation

Automate Acculynx tasks via Rube MCP (Composio). Always search tools first for current schemas.

原文语言：英语

active-campaign-automation

Automate ActiveCampaign tasks via Rube MCP (Composio). Always search tools first for current schemas.

原文语言：英语

addresszen-automation

Automate Addresszen tasks via Rube MCP (Composio). Always search tools first for current schemas.

原文语言：英语

adobe-automation

Automate Adobe tasks via Rube MCP (Composio). Always search tools first for current schemas.

原文语言：英语

adrapid-automation

Automate Adrapid tasks via Rube MCP (Composio). Always search tools first for current schemas.

原文语言：英语