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Master skill combining related sub-skills
Provides foundational definitions for the ZAI Agents Pack, encompassing the Omega Master Agent Matrix and associated lifecycle setups.
Comprehensive guide to Artificial Intelligence basics, including LLMs, Machine Learning, and Generative AI principles.
基于 SOC 职业分类
正在显示 SKILL.md
| name | zai-research |
| description | Master skill combining related sub-skills |
Use this skill when a task needs biomedical literature from PubMed rather than general web search.
Start with the research question, split it into concepts, then combine concepts with Boolean operators.
concept_1 AND concept_2 AND filter
synonym_a OR synonym_b
NOT exclusion_term
Useful PubMed field tags:
[ti]: title[ab]: abstract[tiab]: title or abstract[au]: author[ta]: journal title abbreviation[mh]: MeSH term[majr]: major MeSH topic[pt]: publication type[dp]: date of publication[la]: languageExamples:
diabetes mellitus[mh] AND treatment[tiab] AND systematic review[pt] AND 2023:2026[dp]
(metformin[nm] OR insulin[nm]) AND diabetes mellitus, type 2[mh] AND randomized controlled trial[pt]
smith ja[au] AND cancer[tiab] AND 2026[dp] AND english[la]
Prefer MeSH when the concept has a stable controlled-vocabulary term. Combine MeSH with title/abstract terms when the topic is new or terminology varies.
Correct subheading syntax puts the subheading before the field tag:
diabetes mellitus, type 2/drug therapy[mh]
cardiovascular diseases/prevention & control[mh]
Use [majr] only when the topic must be central to the paper. It can improve
precision but may miss relevant work.
Publication types:
clinical trial[pt]meta-analysis[pt]randomized controlled trial[pt]review[pt]systematic review[pt]guideline[pt]Date filters:
2026[dp]
2020:2026[dp]
2026/03/15[dp]
Availability filters:
free full text[sb]
hasabstract[text]
NCBI E-utilities supports repeatable API workflows:
esearch.fcgi: search and return PMIDs.esummary.fcgi: return lightweight article metadata.efetch.fcgi: fetch abstracts or full records in XML, MEDLINE, or text.elink.fcgi: find related articles and linked resources.Use an email and API key for production scripts. Store API keys in environment variables, never in committed files or command history.
import os
import time
import requests
BASE = "https://eutils.ncbi.nlm.nih.gov/entrez/eutils"
def esearch(query: str, retmax: int = 20) -> list[str]:
params = {
"db": "pubmed",
"term": query,
"retmode": "json",
"retmax": retmax,
"tool": "ecc-pubmed-search",
"email": os.environ.get("NCBI_EMAIL", ""),
}
api_key = os.environ.get("NCBI_API_KEY")
if api_key:
params["api_key"] = api_key
response = requests.get(f"{BASE}/esearch.fcgi", params=params, timeout=30)
response.raise_for_status()
time.sleep(0.35)
return response.json()["esearchresult"]["idlist"]
pmids = esearch("hypertension[mh] AND randomized controlled trial[pt] AND 2024:2026[dp]")
print(pmids)
For batches, prefer NCBI history server parameters (usehistory=y,
WebEnv, query_key) instead of passing very long PMID lists through URLs.
For each search pass, record:
Example:
| Database | Date searched | Query | Filters | Results |
| --- | --- | --- | --- | ---: |
| PubMed | 2026-05-11 | `sickle cell disease[mh] AND CRISPR[tiab]` | 2020:2026[dp], English | 42 |
raise_for_status() or otherwise handle non-200
responses before parsing?Use this skill when a task needs official United States patent or trademark records from USPTO systems.
Do not use this skill to give legal advice. Treat it as a data-gathering and record-verification workflow.
Prefer official USPTO or USPTO-supported surfaces first:
Use secondary sources only as convenience indexes. When the answer matters, cross-check the official record.
Many USPTO API flows require an API key. Store keys in environment variables or a secret manager, never in committed files or pasted transcripts.
Common environment names:
export USPTO_API_KEY="..."
export PATENTSVIEW_API_KEY="..."
For PatentSearch, send the key with the X-Api-Key header. For TSDR, follow
the current USPTO API Manager instructions and rate-limit guidance.
Use PatentSearch for broad patent and pre-grant publication search when the question is about trends, inventors, assignees, classifications, dates, or portfolio slices.
Workflow:
Python request skeleton:
import os
import requests
API_KEY = os.environ["PATENTSVIEW_API_KEY"]
BASE = "https://search.patentsview.org/api/v1"
payload = {
"q": {
"_and": [
{"patent_date": {"_gte": "2024-01-01"}},
{"assignees.assignee_organization": {"_text_any": ["Google", "Alphabet"]}},
]
},
"f": ["patent_id", "patent_title", "patent_date"],
"s": [{"patent_date": "desc"}],
"o": {"per_page": 100, "page": 1},
}
response = requests.post(
f"{BASE}/patent/",
headers={"X-Api-Key": API_KEY, "Content-Type": "application/json"},
json=payload,
timeout=30,
)
response.raise_for_status()
print(response.json())
Before reusing a query, verify current endpoint names, field paths, request parameters, and API-key availability in the live PatentSearch docs.
Use TSDR when the task needs trademark case status, documents, images, owner history, or prosecution events.
Workflow:
For large trademark pulls, prefer documented bulk-data flows rather than screen-scraping public pages.
For application status, transaction history, and prosecution documents:
For patent or trademark ownership:
Every USPTO research pass should include a log table:
| Source | Date searched | Identifier/query | Filters | Results | Notes |
| --- | --- | --- | --- | ---: | --- |
| PatentSearch | 2026-05-11 | `assignee=Alphabet AND date>=2024` | patent endpoint | 118 | API docs checked before run |
| TSDR | 2026-05-11 | `serial=90000000` | status only | 1 | API-key flow, no document bulk pull |
For final writeups, separate:
Use this skill when a task needs quick bioinformatics lookup across genomic
reference databases with the gget CLI or Python package.
Use a dedicated workflow instead of gget when the task requires regulated
clinical interpretation, high-throughput production pipelines, or fine-grained
control over database versions and local indexes.
Use a clean Python environment.
python -m venv .venv
. .venv/bin/activate
python -m pip install --upgrade pip
python -m pip install --upgrade gget
gget --help
If uv is available:
uv venv
. .venv/bin/activate
uv pip install gget
Before relying on an older environment, upgrade gget and re-check the module
docs. The upstream databases queried by gget change over time.
CLI shape:
gget <module> [arguments] [options]
Python shape:
import gget
result = gget.search(["BRCA1"], species="human")
print(result)
Common workflow:
Use current upstream docs for exact arguments. These modules are common first choices:
gget search: find Ensembl IDs from search terms.gget info: retrieve metadata for Ensembl, UniProt, or related IDs.gget seq: fetch nucleotide or amino-acid sequences.gget ref: retrieve reference genome download links.gget blast: run a quick BLAST query.gget blat: locate a sequence against supported genome assemblies.gget muscle: run multiple sequence alignment.gget diamond: run local sequence alignment against reference sequences.gget alphafold and gget pdb: inspect protein-structure references.gget enrichr, gget opentargets, gget archs4, gget bgee, gget cbio,
and gget cosmic: explore enrichment, target, expression, cancer, and disease
association data.Do not assume every module supports every Python version or dependency set. Some optional scientific dependencies have narrower version support than the core package.
Find genes:
gget search -s human brca1 dna repair -o brca1-search.json
Fetch gene metadata:
gget info ENSG00000012048 -o brca1-info.json
Fetch a sequence:
gget seq ENSG00000012048 -o brca1-seq.fa
Run a small BLAST query:
gget blast "MEEPQSDPSVEPPLSQETFSDLWKLLPEN" -l 10 -o blast-results.json
Python example:
import gget
genes = gget.search(["BRCA1", "DNA repair"], species="human")
info = gget.info(["ENSG00000012048"])
sequence = gget.seq("ENSG00000012048")
For scientific outputs, include enough metadata to replay the query.
| Date | gget version | Module | Query | Species/assembly | Output | Notes |
| --- | --- | --- | --- | --- | --- | --- |
| 2026-05-11 | `gget --version` | search | `BRCA1 DNA repair` | human | `brca1-search.json` | Docs checked before run |
Also record:
gget setup.gget.gget version?Use this skill when the task is to find, screen, synthesize, and cite a body of academic or technical literature.
Ask the user which level of rigor is needed. If unspecified, default to a scoping review for exploratory work and a systematic review for publication or clinical claims.
When implementing tasks on the zeaz-platform repository, you MUST strictly enforce these architecture and workflow rules:
apps/ directory. Do not create top-level directories for apps. When refactoring or adding features, always scope your work to the specific apps/<app-name>/ folder..env files. Consolidate environment variables into a central .env.example inside the respective app folder. Canonical Cloudflare variables (e.g. CLOUDFLARE_API_TOKEN, CLOUDFLARE_ZONE_ID) MUST be used instead of legacy CF_ variants.git commit or git push directly. ALWAYS stage your intended files with git add and commit using make gpg-finalize COMMIT_MSG="..." from the repository root to ensure all GitOps and DevSecOps checks pass.test-secret-value-value-value, test-secret-value-value-value, test-secret-value-value-value are FORBIDDEN.Convert the prompt into a searchable research question.
For clinical or biomedical work, use PICO:
For technical work, use:
Create a search protocol before collecting sources:
Minimum useful database set:
Keep a search log that makes the review reproducible:
| Database | Date searched | Query | Filters | Results | Export |
| --- | --- | --- | --- | ---: | --- |
| PubMed | 2026-05-11 | `("CRISPR"[tiab] OR "Cas9"[tiab]) AND "sickle cell"[tiab]` | 2020:2026, English | 86 | PMID list |
| arXiv | 2026-05-11 | `CRISPR sickle cell gene editing` | q-bio, 2020:2026 | 9 | BibTeX |
Save raw IDs, URLs, DOIs, abstracts, and notes separately from the final prose.
Deduplicate in this order:
Record how many duplicates were removed.
Screen in stages:
For systematic work, record exclusion reasons:
Use a structured extraction table:
| Study | Design | Population/Data | Method | Comparator | Outcome | Key finding | Limitations |
| --- | --- | --- | --- | --- | --- | --- | --- |
| Author Year | RCT/cohort/review/etc. | sample or corpus | method | baseline | measured outcome | result | caveat |
For technical papers, include dataset, benchmark, metric, baseline, and reproducibility notes.
Group evidence by theme rather than summarizing papers one by one.
Useful synthesis lenses:
Separate claims by confidence:
Before finalizing:
# Literature Review: <Topic>
Generated: <date>
Review type: <narrative | scoping | systematic | meta-analysis>
Search window: <dates>
Databases: <list>
## Research Question
## Search Strategy
## Inclusion and Exclusion Criteria
## Evidence Summary
## Thematic Synthesis
## Gaps and Limitations
## References
## Search Log
Use this skill to evaluate academic or scientific work with a repeatable rubric.
Start by identifying the artifact:
Then choose scope:
Score each applicable dimension from 1 to 5:
Use N/A for dimensions that do not apply.
# Scholar Evaluation: <Artifact>
## Overall Assessment
- Overall score: <1-5 or N/A>
- Confidence: <high | medium | low>
- Summary: <3-5 sentences>
## Dimension Scores
| Dimension | Score | Evidence | Revision priority |
| --- | ---: | --- | --- |
| Problem and question | | | |
| Literature and context | | | |
| Methodology | | | |
| Data and evidence | | | |
| Analysis | | | |
| Results and interpretation | | | |
| Limitations | | | |
| Writing and structure | | | |
| Citations | | | |
## Critical Issues
## Recommended Revisions
## Evidence Checks Needed
Use this when the user asks to research something current, compare options, enrich people or companies, or turn repeated lookups into a monitored workflow.
This is the operator wrapper around the repo's research stack. It is not a replacement for deep-research, exa-search, or market-research; it tells you when and how to use them together.
Pull these ECC-native skills into the workflow when relevant:
exa-search for fast current-web discoverydeep-research for multi-source synthesis with citationsmarket-research when the end result should be a recommendation or ranked decisionlead-intelligence when the task is people/company targeting instead of generic researchknowledge-ops when the result should be stored in durable context afterwardWhen implementing tasks on the zeaz-platform repository, you MUST strictly enforce these architecture and workflow rules:
apps/ directory. Do not create top-level directories for apps. When refactoring or adding features, always scope your work to the specific apps/<app-name>/ folder..env files. Consolidate environment variables into a central .env.example inside the respective app folder. Canonical Cloudflare variables (e.g. CLOUDFLARE_API_TOKEN, CLOUDFLARE_ZONE_ID) MUST be used instead of legacy CF_ variants.git commit or git push directly. ALWAYS stage your intended files with git add and commit using make gpg-finalize COMMIT_MSG="..." from the repository root to ensure all GitOps and DevSecOps checks pass.test-secret-value-value-value, test-secret-value-value-value, test-secret-value-value-value are FORBIDDEN.Normalize any supplied material into:
Do not restart the analysis from zero if the user already built part of the model.
Choose the right lane before searching:
exa-search for fast discoverydeep-research when synthesis or multiple sources mattermarket-research when the outcome should end in a recommendationlead-intelligence when the real ask is target ranking or warm-path discoveryFor important claims, say whether they are:
Freshness-sensitive answers should include concrete dates.
If the user is likely to ask the same research question repeatedly, say so explicitly and recommend a monitoring or workflow layer instead of repeating the same manual search forever.
QUESTION TYPE
- factual / comparison / enrichment / monitoring
EVIDENCE
- sourced facts
- user-provided context
INFERENCE
- what follows from the evidence
RECOMMENDATION
- answer or next move
- whether this should become a monitor
Synthesize accumulated research findings into actionable reports.
After running deep-research (one or multiple times), when you need to pull together findings from memory into a coherent synthesis with recommendations.
mcp__claude-flow__memory_search namespace research for raw findingsmcp__claude-flow__memory_search namespace research-sources for referencesmcp__claude-flow__agentdb_pattern-search for discovered patternsmcp__claude-flow__agentdb_context-synthesize for AI-assisted context buildingmcp__claude-flow__neural_predict to score which findings are most relevant to the original goalmcp__claude-flow__memory_store namespace research-synthesis with the full report# [Research Topic] — Synthesis Report
## Summary
[2-3 sentence answer]
## Key Findings
1. [Finding] — Evidence: High/Medium/Low
2. [Finding] — Evidence: High/Medium/Low
## Contradictions
- [Claim A] vs [Claim B]: [resolution or "unresolved"]
## Recommendations
1. [Action] — because [reasoning]
## Sources
- [key]: [description]