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ic50-fit
Fit dose-response curves and calculate IC50/EC50 with confidence intervals using 4-parameter logistic regression.
用 Codex 或 Claude 帮你安装 复制这段 Prompt,粘贴到 Codex、Claude 或其他助手里,让它检查 Skill 页面并帮你完成安装。
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Fit dose-response curves and calculate IC50/EC50 with confidence intervals using 4-parameter logistic regression.
用 Codex 或 Claude 帮你安装 复制这段 Prompt,粘贴到 Codex、Claude 或其他助手里,让它检查 Skill 页面并帮你完成安装。
基于 SOC 职业分类
| name | ic50-fit |
| description | Fit dose-response curves and calculate IC50/EC50 with confidence intervals using 4-parameter logistic regression. |
Fit dose-response curves with nonlinear regression.
4-parameter logistic (4PL):
response = bottom + (top - bottom) / (1 + 10^((logIC50 - logConc) * hillSlope))
# Dose-Response: [compound]
## Fitted Parameters
| Parameter | Estimate | 95% CI | SE |
|-----------|----------|--------|-----|
| IC50/EC50 | ... | ... | ... |
| Hill Slope | ... | ... | ... |
| Top | ... | ... | ... |
| Bottom | ... | ... | ... |
## Model Quality
- R²: ...
- Residuals: ...
## Script
[Attach analysis script]
## Plot
[Attach dose-response plot]
Save to outputs/ic50-<slug>.md with script and plot.
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