drug-discovery-skills

Global drug development pipeline tracking by disease, target, mechanism, or company. Use for competitive intelligence, opportunity identification, and trend analysis. Keywords: pipeline, drug development, clinical trials, R&D tracking, competitive landscape

Structure-based similarity search and scaffold analysis for drug discovery. Use for lead hopping, scaffold morphing, and chemical space exploration. Keywords: similarity search, scaffold hopping, chemical space, fingerprint, Tanimoto

Analyze target competitive landscape including existing drugs, pipeline companies, differentiation opportunities, and market maturity assessment. Keywords: target competition, landscape, differentiation, pipeline analysis, market share

Target safety assessment including known toxicities, essentiality, and off-target concerns. Use for early safety risk evaluation and target selection. Keywords: target safety, toxicity, essential gene, knockout, safety risks

Comprehensive target validation assessing druggability, disease association strength, tractability, and competitive landscape. Use for go/no-go decisions on target selection. Keywords: target validation, druggability, tractability, disease association, genetic validation

ADMET (Absorption, Distribution, Metabolism, Excretion, Toxicity) prediction for drug candidates. Use for assessing drug-likeness, PK properties, and safety risks early in drug discovery. Keywords: ADMET, PK, toxicity, drug-likeness, DILI, hERG, bioavailability

Automated alert system for key events in drug discovery. Use for tracking competitor milestones, clinical trial updates, regulatory decisions, and publications of interest. Keywords: alerts, monitoring, tracking, notifications, competitive intelligence

Deep analysis of clinical trials including design, enrollment, outcomes, and competitive positioning. Use for trial monitoring, landscape analysis, and competitive intelligence. Keywords: clinical, trials, NCT, enrollment, phase, outcomes, study design

Analyze competitive landscape for drugs including clinical pipeline, mechanism of action, development status, and company profiles. Use this skill for competitive intelligence, pipeline tracking, market analysis, and investment due diligence. Supports drug names, target areas, or disease indications. Keywords: competitor, competition, landscape, pipeline, drugs, market analysis

Generate comprehensive compound profiles including structure, properties, bioactivity, and development status. Use for drug analysis, SAR studies, and competitive profiling. Keywords: compound, drug, molecule, structure, SMILES, bioactivity, IC50

Track pharmaceutical M&A, licensing, and investment deals. Use for competitive intelligence, market analysis, and identifying partnership opportunities. Keywords: deals, M&A, licensing, partnership, collaboration, acquisition, pharma deals

Comprehensive literature search with automatic summarization, trend analysis, and key paper identification from PubMed and preprints. Use this skill for literature review, trend identification, key paper discovery, and staying current with research developments. Keywords: literature, pubmed, papers, search, bibliography, review

Market sizing, epidemiology, and commercial opportunity assessment for drug development. Use for market forecasts, opportunity evaluation, and investment decisions. Keywords: market, epidemiology, prevalence, forecast, sizing, opportunity

Search and analyze patents including FTO (Freedom to Operate) analysis, patent landscape mapping, and competitive IP intelligence. Keywords: patent, FTO, freedom to operate, IP, intellectual property

Generate professional drug discovery reports including target dossiers, competitive briefs, and Go/No-Go decision summaries. Use this skill when you need formatted reports for presentations, decision meetings, or documentation. Supports multiple output formats. Keywords: report, dossier, decision, go-no-go, brief, presentation

Generate comprehensive target profiles including druggability assessment, disease associations, pathway context, and competitive landscape. Use this skill when analyzing drug targets for validation, dossier creation, or competitive intelligence. Supports gene symbols (EGFR), protein names, or UniProt IDs. Keywords: target, dossier, validation, druggability, tractability, target analysis

Molecular docking and virtual screening for drug discovery. Use for screening compound libraries against protein targets, predicting binding affinities, and identifying lead candidates. Keywords: docking, virtual screening, molecular docking, binding affinity, lead identification