| name | prismalab-systematic-review |
| description | Conduct PRISMA 2020-compliant systematic reviews using Azure AI services. Covers protocol development, search strategy, screening, and reporting. |
PrismaLab Systematic Review Skill
When to Use
- User asks to plan or conduct a systematic review
- User needs a search strategy for databases (PubMed, Cochrane, Embase)
- User needs PRISMA 2020 checklist compliance
- User asks about inclusion/exclusion criteria
Azure Services Used
- Azure AI Foundry (
ipai-copilot-resource): GPT-4.1 for protocol drafting, search strategy generation
- Azure AI Search (
srch-ipai-dev-sea, index: prismalab-rag-v1): RAG over methodology corpus
- PubMed MCP (via Claude.ai connector): Live database searching
Workflow
Step 1: Protocol Development
Generate a PROSPERO-ready protocol from a research question:
Input: "What is the effectiveness of AI-assisted diagnosis in diabetic retinopathy?"
Output: Structured protocol with PICO, objectives, search strategy, eligibility criteria
Step 2: Search Strategy
Generate database-specific search strings:
search = {
"population": "diabetic retinopathy patients",
"intervention": "artificial intelligence OR deep learning OR machine learning",
"comparator": "ophthalmologist OR human expert",
"outcome": "diagnostic accuracy OR sensitivity OR specificity",
"filters": ["humans", "english", "2019-2026"]
}
Use Boolean operators adapted per database:
- PubMed: MeSH terms + free text with [tiab]
- Cochrane: MeSH + explosion
- Embase: Emtree terms
Step 3: Screening
Two-phase screening approach:
- Title/Abstract screening: Use GPT-4.1 to pre-classify relevance (human confirms)
- Full-text screening: Azure Document Intelligence extracts text from PDFs, GPT-4.1 assesses eligibility
Step 4: PRISMA Flow Diagram
Generate the PRISMA 2020 flow diagram data:
Records identified (n=X)
→ Duplicates removed (n=X)
→ Screened (n=X)
→ Excluded (n=X)
→ Full-text assessed (n=X)
→ Excluded with reasons (n=X)
→ Included in synthesis (n=X)
→ Quantitative synthesis (n=X)
Quality Standards
- Always register protocol in PROSPERO before screening
- Minimum two independent reviewers for screening (AI can be one, human must be other)
- Report inter-rater reliability (Cohen's kappa)
- Follow PRISMA 2020 27-item checklist
- Declare AI assistance in methods section
Limitations
- AI screening is assistive, not authoritative
- Always validate AI-generated search strategies with a librarian
- Full-text PDFs require publisher access (not all are open access)
