| name | KSB-D02-K0002 |
| description | Type B Reactions: Dose-independent, unpredictable, idiosyncratic responses... |
| version | 1.0.0 |
| domain | D02 |
| domain_name | Clinical Aspects of ADRs |
| type | Knowledge |
| proficiency_level | L3 |
| bloom_level | apply |
| triggers | ["explain type b reactions","what is type b reactions","apply type b reactions"] |
| epa_mapping | EPA-01, EPA-02, EPA-05 |
| cpa_mapping | CPA-01, CPA-02 |
| regulatory_refs | ICH-E2A, FDA-GUID-001 |
KSB-D02-K0002: Type B Reactions
Overview
Domain: D02 - Clinical Aspects of ADRs
Type: Knowledge
Proficiency Level: L3 (Competent - Minimal supervision)
Bloom Level: Apply
Description
Dose-independent, unpredictable, idiosyncratic responses
Context
- Major Section: ADR Classification Systems
- Section: ADR Classification Systems
EPA Mapping
- EPA-01:3001-3003
- EPA-02:3004-3005
- EPA-05:3011-3012
CPA Pathway
Regulatory References
Instructions
When this skill is activated, Claude should:
- Demonstrate L3 proficiency in type b reactions
- Apply apply level cognitive skills to apply the topic
- Reference relevant regulatory guidance (ICH-E2A, FDA-GUID-001)
- Connect to related EPAs: EPA-01, EPA-02, EPA-05
Key Competencies
- Dose-independent, unpredictable, idiosyncratic responses
Assessment Criteria
- Can apply core concepts independently
- Demonstrates understanding of regulatory context
- Applies knowledge appropriately to PV scenarios
Related Skills
- Other D02 skills in ADR Classification Systems
- Cross-domain integrations per DAG architecture
Generated from PV KSB Framework v1.0 | 2025-12-31
