protein-engineering-hypothesis

Evidence-bounded hypothesis and experiment planning for protein engineering. Use when the user asks what to mutate next, how to prioritize variants, how to falsify a mechanism, or how to design a directed-evolution round. Do NOT invent wet-lab results; chain VenusFactory tools for computational evidence and label model scores as hypotheses.

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Repositorio: ai4protein/VenusFactory2
Última actividad en el origen: 28 de julio de 2026 a las 05:29
Idioma detectado de SKILL.md: inglés
Estrellas: 248
Forks: 36

Opciones de instalación

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npx skills add https://github.com/ai4protein/VenusFactory2 --skill protein-engineering-hypothesis

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venus-finetune-workflow

Fine-tune and run custom protein models on VenusFactory (CSV/HF → config → train → predict). Use when the user brings labeled sequences, wants adapter training (ProtT5/ESM2/Ankh/QLoRA notes), or batch inference with a trained config. Do NOT use for zero-shot mutation without labels (zero_shot_mutation_workflow) or built-in function heads already covered by predict_protein_function.

2026-07-28

alphafold-database

AlphaFold DB structures and confidence analytics via VenusFactory tools. Use when the user needs predicted structures by UniProt ID, pLDDT/PAE analysis, or PDB/mmCIF download. Do NOT use for experimental PDB (rcsb_database), local ESMFold without UniProt (predict_structure_esmfold / protein_structure_pipeline), or sequence annotation (uniprot_database).

2026-07-28

arxiv

arXiv preprint server — keyword search the official API and download papers as PDF / HTML / source tarball. Use whenever the user mentions an arXiv ID (e.g. 2106.04559) or wants preprints on a topic in CS / physics / math / quantitative biology. For biomedical preprints specifically, prefer biorxiv skill.

2026-07-28

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name	protein_engineering_hypothesis
description	Evidence-bounded hypothesis and experiment planning for protein engineering. Use when the user asks what to mutate next, how to prioritize variants, how to falsify a mechanism, or how to design a directed-evolution round. Do NOT invent wet-lab results; chain VenusFactory tools for computational evidence and label model scores as hypotheses.
license	Apache-2.0
metadata	{"version":"1.0","skill-author":"VenusFactory2"}