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O SkillsMP coletou 858 skills de dromlakhani/MD2SKILL. Abra uma skill para revisar a origem e os detalhes.
dromlakhani/MD2SKILLMostrando 40 de 858 skills coletadas.
This skill advises initiation of statin as adjunct to diet and exercise after discussion of risks/benefits when LDL-C >70 mg/dL and 10-year ASCVD risk >7.5%, or ASCVD risk 5% to 7.4% plus 1+ risk-enhancing factors, or CAC score >75th percentile for…
Idioma do texto original: inglês
The guideline recommends statin therapy over hormone therapy for dyslipidemia management in postmenopausal women. Consider this approach when encountering a postmenopausal woman with dyslipidemia, choosing between statin and hormone therapy, or assessing…
Idioma do texto original: inglês
Recommends considering renal clearance when selecting a statin in chronic kidney disease, preferring pitavastatin, pravastatin, and rosuvastatin which have partial kidney clearance over atorvastatin, fluvastatin, lovastatin, and simvastatin which are cleared…
Idioma do texto original: inglês
This skill suggests statin therapy as adjunct to lifestyle modification to reduce cardiovascular risk in adults with persistent endogenous Cushing syndrome, irrespective of cardiovascular risk score. Trigger phrases include "Patient with persistent Cushing…
Idioma do texto original: inglês
Recommends statin therapy to reduce cardiovascular risk in postmenopausal women on hormone therapy who have additional cardiovascular risk factors. Trigger phrases include: "Postmenopausal woman on HRT with CVD risk factors", "Assessing statin need in…
Idioma do texto original: inglês
This skill suggests statin therapy, irrespective of cardiovascular risk score, to reduce cardiovascular risk in adults with type 1 diabetes who are age 40 years or older, have diabetes duration >20 years, or have microvascular complications. Clinical triggers…
Idioma do texto original: inglês
This skill suggests statin therapy irrespective of cardiovascular risk score to reduce cardiovascular risk in adults with type 1 diabetes and chronic kidney disease stages 1-4. Clinical triggers include "Patient with T1D and CKD stages 1-4", "Assessing statin…
Idioma do texto original: inglês
Suggests statin therapy, irrespective of the cardiovascular risk score, to reduce cardiovascular risk in adults with type 1 diabetes and diabetic retinopathy. Trigger phrases include "Patient with T1D and diabetic retinopathy", "Considering statin for T1D…
Idioma do texto original: inglês
Suggests statin therapy, irrespective of the cardiovascular risk score, to reduce cardiovascular risk in adults with type 1 diabetes who have obesity or who have high triglycerides and low HDL-C. Clinical triggers include "T1D patient with obesity", "T1D with…
Idioma do texto original: inglês
This skill suggests statin therapy irrespective of cardiovascular risk score to reduce cardiovascular risk in adults with type 2 diabetes and CKD stages 1-4 or postrenal transplant. Consider when encountering phrases such as "Patient with T2D and CKD stages…
Idioma do texto original: inglês
Recommends statin therapy in addition to lifestyle modification to reduce cardiovascular risk in adults with type 2 diabetes and additional cardiovascular risk factors such as hypertension, dyslipidemia, smoking, or family history of premature ASCVD. Use when…
Idioma do texto original: inglês
This skill recommends checking triglyceride levels before and after starting a bile acid sequestrant in patients with elevated triglycerides (150-499 mg/dL). Clinical triggers include: triglyceride level 150-499 mg/dL, consideration of bile acid sequestrant…
Idioma do texto original: inglês
Suggests the use of analgesics as adjunctive therapy for mild-to-moderate joint pain due to joint cartilage deterioration in patients with Paget's disease adjacent to the painful joint. Triggered when a patient reports joint pain attributable to adjacent…
Idioma do texto original: inglês
The guideline recommends using biochemical follow-up as a more objective indicator of relapse than symptoms in patients with increased bone turnover after treatment for Paget’s disease. Trigger phrases include monitoring for disease recurrence after…
Idioma do texto original: inglês
This skill suggests treatment with a bisphosphonate in patients with Paget's disease who also have symptomatic congestive heart failure. Triggers include the presence of Paget's disease alongside signs or symptoms of congestive heart failure such as dyspnea,…
Idioma do texto original: inglês
Pretreat with a potent bisphosphonate before surgery for pagetic bone neoplasm to reduce bleeding from adjacent pagetic bone. Triggers include suspicion of osteosarcoma or giant cell tumor in pagetic bone prompting orthopedic surgical referral.
Idioma do texto original: inglês
This skill recommends immediate administration of a potent intravenous bisphosphonate with neurosurgical consultation for patients presenting with paraplegia or progressive spinal stenosis attributable to spinal Paget's disease. Clinical triggers include…
Idioma do texto original: inglês
This skill suggests administering a bisphosphonate before elective total joint replacement to reduce intraoperative hemorrhaging and postoperative loosening of the prosthesis in patients with severe osteoarthritis adjacent to Paget's disease bone. Trigger…
Idioma do texto original: inglês
Recommends administering a potent bisphosphonate prior to elective osteotomy for severe lower‑extremity bowing in Paget’s disease that causes impaired ambulation or severe joint pain. Triggered when planning surgical correction of a lower‑extremity deformity…
Idioma do texto original: inglês
Recommends treatment with a bisphosphonate for most patients with active Paget's disease who are at risk of future complications. Triggers include active Paget's disease with risk of fracture, deformity, or neurologic symptoms.
Idioma do texto original: inglês
Recommends measuring a specific bone formation or resorption marker in patients with Paget's disease who have abnormal liver or biliary tract function to assess treatment response or disease evolution. Triggered when liver function tests (e.g., ALT, AST, ALP,…
Idioma do texto original: inglês
This skill outlines using short-term changes in bone resorption markers (e.g., serum CTx or urine NTx) before and shortly after bisphosphonate therapy to predict an adequate therapeutic response. It is triggered when there is urgency to control severe…
Idioma do texto original: inglês
Suggests treatment with a potent bisphosphonate to prevent worsening of a hearing deficit in patients with Paget's disease involving the temporal bone. Triggers include detected or suspected hearing loss thought to be related to Paget's disease.
Idioma do texto original: inglês
Recommends obtaining serum total alkaline phosphatase or a more specific bone formation marker for initial biochemical evaluation after radiological confirmation of Paget’s disease. Triggered after imaging establishes diagnosis to set baseline bone turnover.
Idioma do texto original: inglês
Uses the least significant change (LSC) derived from analytical and biological variation to determine whether two sequential bone turnover marker measurements reflect a true biological difference. Triggers include when monitoring biomarker trends to assess…
Idioma do texto original: inglês
Assesses biochemical activity in untreated monostotic Paget's disease by measuring P1NP or BSAP and CTx or NTx when scintigraphy shows disease activity despite normal total alkaline phosphatase. Triggered when evaluating disease activity in patients with…
Idioma do texto original: inglês
Recommends obtaining plain radiographs of the suspicious regions of the skeleton in patients with suspected Paget's disease. Clinical triggers include unexplained bone pain, elevated alkaline phosphatase, or clinical suspicion based on presentation.
Idioma do texto original: inglês
This skill suggests performing a radionuclide bone scan to determine the extent of Paget's disease and identify asymptomatic sites after diagnosis. It is triggered when Paget's disease is diagnosed and a baseline extent assessment is needed.
Idioma do texto original: inglês
Suggests reducing bone turnover below the midpoint of the reference range for the chosen monitoring bone turnover marker to maximize the duration of remission. Triggered when aiming to sustain long-term remission after treatment and the marker exceeds the…
Idioma do texto original: inglês
This skill outlines when to obtain a repeat radiograph approximately one year after radiological diagnosis of osteolytic lesions in Paget's disease to assess lesion improvement or worsening. Consider repeat imaging if biochemical markers of bone turnover…
Idioma do texto original: inglês
This skill determines the appropriate retreatment interval for bisphosphonate therapy in Paget's disease based on drug-specific remission duration. It is triggered when planning long-term management after an initial bisphosphonate course, considering…
Idioma do texto original: inglês
Suggests a single 5‑mg intravenous dose of zoledronate as the treatment of choice in patients with active Paget’s disease who have no contraindication to IV zoledronate. Triggered when initiating pharmacologic therapy for Paget’s disease and confirming…
Idioma do texto original: inglês
Orders mandatory MRI, contrast CT, and somatostatin receptor nuclear imaging when a non-catecholamine-producing pheochromocytoma or paraganglioma is suspected based on imaging findings with normal fractionated metanephrines and catecholamines. Considers SDHD…
Idioma do texto original: inglês
Investigates for pheochromocytoma and paraganglioma in children presenting with hypertension plus symptoms such as headache, excessive sweating, or palpitations. Notes the absence of pediatric reference values for endocrine tests and selects tumor resection…
Idioma do texto original: inglês
Recommends against fine needle cytology for pathological diagnosis of head and neck paraganglioma due to its low accuracy and risk of misdiagnosis. Use when a clinician asks 'Should I perform fine needle cytology for suspected head and neck paraganglioma?' —…
Idioma do texto original: inglês
This skill guides the use of biomarkers to prognosticate metastatic pheochromocytoma and paraganglioma (PPGL) by applying independent prognostic factors such as older age, larger tumor size, metastases at diagnosis, multiple metastases, high chromogranin A,…
Idioma do texto original: inglês
This skill guides management of bone metastases in pheochromocytoma and paraganglioma, recommending external radiation therapy and surgical approaches similar to other solid cancers. It is triggered by known or suspected bone metastases, spinal cord…
Idioma do texto original: inglês
Recommends CVD chemotherapy as first-line systemic treatment for unresectable pheochromocytoma/paraganglioma with rapid progression or when radionuclide therapy is not applicable. Considers disease progression rate and feasibility to choose between CVD…
Idioma do texto original: inglês
Selects the appropriate confirmatory test after a positive pheochromocytoma/paraganglioma (PPGL) screening test. Triggers include elevated random urinary metanephrines (>3× ULN after creatinine correction), blood catecholamines (>3× ULN), or plasma-free…
Idioma do texto original: inglês
Recommends stereotactic radiotherapy for local control of head and neck paraganglioma and postoperative radiotherapy for incompletely resectable spinal paraganglioma; considers external beam radiation therapy for local control of pheochromocytoma and…
Idioma do texto original: inglês