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SkillsMP hat 858 Skills aus dromlakhani/MD2SKILL gesammelt. Öffne einen Skill, um Quelle und Details zu prüfen.
dromlakhani/MD2SKILLEs werden 40 von 858 gesammelten Skills angezeigt.
This skill advises initiation of statin as adjunct to diet and exercise after discussion of risks/benefits when LDL-C >70 mg/dL and 10-year ASCVD risk >7.5%, or ASCVD risk 5% to 7.4% plus 1+ risk-enhancing factors, or CAC score >75th percentile for…
Quellsprache: Englisch
The guideline recommends statin therapy over hormone therapy for dyslipidemia management in postmenopausal women. Consider this approach when encountering a postmenopausal woman with dyslipidemia, choosing between statin and hormone therapy, or assessing…
Quellsprache: Englisch
Recommends considering renal clearance when selecting a statin in chronic kidney disease, preferring pitavastatin, pravastatin, and rosuvastatin which have partial kidney clearance over atorvastatin, fluvastatin, lovastatin, and simvastatin which are cleared…
Quellsprache: Englisch
This skill suggests statin therapy as adjunct to lifestyle modification to reduce cardiovascular risk in adults with persistent endogenous Cushing syndrome, irrespective of cardiovascular risk score. Trigger phrases include "Patient with persistent Cushing…
Quellsprache: Englisch
Recommends statin therapy to reduce cardiovascular risk in postmenopausal women on hormone therapy who have additional cardiovascular risk factors. Trigger phrases include: "Postmenopausal woman on HRT with CVD risk factors", "Assessing statin need in…
Quellsprache: Englisch
This skill suggests statin therapy, irrespective of cardiovascular risk score, to reduce cardiovascular risk in adults with type 1 diabetes who are age 40 years or older, have diabetes duration >20 years, or have microvascular complications. Clinical triggers…
Quellsprache: Englisch
This skill suggests statin therapy irrespective of cardiovascular risk score to reduce cardiovascular risk in adults with type 1 diabetes and chronic kidney disease stages 1-4. Clinical triggers include "Patient with T1D and CKD stages 1-4", "Assessing statin…
Quellsprache: Englisch
Suggests statin therapy, irrespective of the cardiovascular risk score, to reduce cardiovascular risk in adults with type 1 diabetes and diabetic retinopathy. Trigger phrases include "Patient with T1D and diabetic retinopathy", "Considering statin for T1D…
Quellsprache: Englisch
Suggests statin therapy, irrespective of the cardiovascular risk score, to reduce cardiovascular risk in adults with type 1 diabetes who have obesity or who have high triglycerides and low HDL-C. Clinical triggers include "T1D patient with obesity", "T1D with…
Quellsprache: Englisch
This skill suggests statin therapy irrespective of cardiovascular risk score to reduce cardiovascular risk in adults with type 2 diabetes and CKD stages 1-4 or postrenal transplant. Consider when encountering phrases such as "Patient with T2D and CKD stages…
Quellsprache: Englisch
Recommends statin therapy in addition to lifestyle modification to reduce cardiovascular risk in adults with type 2 diabetes and additional cardiovascular risk factors such as hypertension, dyslipidemia, smoking, or family history of premature ASCVD. Use when…
Quellsprache: Englisch
This skill recommends checking triglyceride levels before and after starting a bile acid sequestrant in patients with elevated triglycerides (150-499 mg/dL). Clinical triggers include: triglyceride level 150-499 mg/dL, consideration of bile acid sequestrant…
Quellsprache: Englisch
Suggests the use of analgesics as adjunctive therapy for mild-to-moderate joint pain due to joint cartilage deterioration in patients with Paget's disease adjacent to the painful joint. Triggered when a patient reports joint pain attributable to adjacent…
Quellsprache: Englisch
The guideline recommends using biochemical follow-up as a more objective indicator of relapse than symptoms in patients with increased bone turnover after treatment for Paget’s disease. Trigger phrases include monitoring for disease recurrence after…
Quellsprache: Englisch
This skill suggests treatment with a bisphosphonate in patients with Paget's disease who also have symptomatic congestive heart failure. Triggers include the presence of Paget's disease alongside signs or symptoms of congestive heart failure such as dyspnea,…
Quellsprache: Englisch
Pretreat with a potent bisphosphonate before surgery for pagetic bone neoplasm to reduce bleeding from adjacent pagetic bone. Triggers include suspicion of osteosarcoma or giant cell tumor in pagetic bone prompting orthopedic surgical referral.
Quellsprache: Englisch
This skill recommends immediate administration of a potent intravenous bisphosphonate with neurosurgical consultation for patients presenting with paraplegia or progressive spinal stenosis attributable to spinal Paget's disease. Clinical triggers include…
Quellsprache: Englisch
This skill suggests administering a bisphosphonate before elective total joint replacement to reduce intraoperative hemorrhaging and postoperative loosening of the prosthesis in patients with severe osteoarthritis adjacent to Paget's disease bone. Trigger…
Quellsprache: Englisch
Recommends administering a potent bisphosphonate prior to elective osteotomy for severe lower‑extremity bowing in Paget’s disease that causes impaired ambulation or severe joint pain. Triggered when planning surgical correction of a lower‑extremity deformity…
Quellsprache: Englisch
Recommends treatment with a bisphosphonate for most patients with active Paget's disease who are at risk of future complications. Triggers include active Paget's disease with risk of fracture, deformity, or neurologic symptoms.
Quellsprache: Englisch
Recommends measuring a specific bone formation or resorption marker in patients with Paget's disease who have abnormal liver or biliary tract function to assess treatment response or disease evolution. Triggered when liver function tests (e.g., ALT, AST, ALP,…
Quellsprache: Englisch
This skill outlines using short-term changes in bone resorption markers (e.g., serum CTx or urine NTx) before and shortly after bisphosphonate therapy to predict an adequate therapeutic response. It is triggered when there is urgency to control severe…
Quellsprache: Englisch
Suggests treatment with a potent bisphosphonate to prevent worsening of a hearing deficit in patients with Paget's disease involving the temporal bone. Triggers include detected or suspected hearing loss thought to be related to Paget's disease.
Quellsprache: Englisch
Recommends obtaining serum total alkaline phosphatase or a more specific bone formation marker for initial biochemical evaluation after radiological confirmation of Paget’s disease. Triggered after imaging establishes diagnosis to set baseline bone turnover.
Quellsprache: Englisch
Uses the least significant change (LSC) derived from analytical and biological variation to determine whether two sequential bone turnover marker measurements reflect a true biological difference. Triggers include when monitoring biomarker trends to assess…
Quellsprache: Englisch
Assesses biochemical activity in untreated monostotic Paget's disease by measuring P1NP or BSAP and CTx or NTx when scintigraphy shows disease activity despite normal total alkaline phosphatase. Triggered when evaluating disease activity in patients with…
Quellsprache: Englisch
Recommends obtaining plain radiographs of the suspicious regions of the skeleton in patients with suspected Paget's disease. Clinical triggers include unexplained bone pain, elevated alkaline phosphatase, or clinical suspicion based on presentation.
Quellsprache: Englisch
This skill suggests performing a radionuclide bone scan to determine the extent of Paget's disease and identify asymptomatic sites after diagnosis. It is triggered when Paget's disease is diagnosed and a baseline extent assessment is needed.
Quellsprache: Englisch
Suggests reducing bone turnover below the midpoint of the reference range for the chosen monitoring bone turnover marker to maximize the duration of remission. Triggered when aiming to sustain long-term remission after treatment and the marker exceeds the…
Quellsprache: Englisch
This skill outlines when to obtain a repeat radiograph approximately one year after radiological diagnosis of osteolytic lesions in Paget's disease to assess lesion improvement or worsening. Consider repeat imaging if biochemical markers of bone turnover…
Quellsprache: Englisch
This skill determines the appropriate retreatment interval for bisphosphonate therapy in Paget's disease based on drug-specific remission duration. It is triggered when planning long-term management after an initial bisphosphonate course, considering…
Quellsprache: Englisch
Suggests a single 5‑mg intravenous dose of zoledronate as the treatment of choice in patients with active Paget’s disease who have no contraindication to IV zoledronate. Triggered when initiating pharmacologic therapy for Paget’s disease and confirming…
Quellsprache: Englisch
Orders mandatory MRI, contrast CT, and somatostatin receptor nuclear imaging when a non-catecholamine-producing pheochromocytoma or paraganglioma is suspected based on imaging findings with normal fractionated metanephrines and catecholamines. Considers SDHD…
Quellsprache: Englisch
Investigates for pheochromocytoma and paraganglioma in children presenting with hypertension plus symptoms such as headache, excessive sweating, or palpitations. Notes the absence of pediatric reference values for endocrine tests and selects tumor resection…
Quellsprache: Englisch
Recommends against fine needle cytology for pathological diagnosis of head and neck paraganglioma due to its low accuracy and risk of misdiagnosis. Use when a clinician asks 'Should I perform fine needle cytology for suspected head and neck paraganglioma?' —…
Quellsprache: Englisch
This skill guides the use of biomarkers to prognosticate metastatic pheochromocytoma and paraganglioma (PPGL) by applying independent prognostic factors such as older age, larger tumor size, metastases at diagnosis, multiple metastases, high chromogranin A,…
Quellsprache: Englisch
This skill guides management of bone metastases in pheochromocytoma and paraganglioma, recommending external radiation therapy and surgical approaches similar to other solid cancers. It is triggered by known or suspected bone metastases, spinal cord…
Quellsprache: Englisch
Recommends CVD chemotherapy as first-line systemic treatment for unresectable pheochromocytoma/paraganglioma with rapid progression or when radionuclide therapy is not applicable. Considers disease progression rate and feasibility to choose between CVD…
Quellsprache: Englisch
Selects the appropriate confirmatory test after a positive pheochromocytoma/paraganglioma (PPGL) screening test. Triggers include elevated random urinary metanephrines (>3× ULN after creatinine correction), blood catecholamines (>3× ULN), or plasma-free…
Quellsprache: Englisch
Recommends stereotactic radiotherapy for local control of head and neck paraganglioma and postoperative radiotherapy for incompletely resectable spinal paraganglioma; considers external beam radiation therapy for local control of pheochromocytoma and…
Quellsprache: Englisch