conservation-map
Compute per-position conservation/entropy for an aligned peptide MSA (aligned sequences).
Source facts
- Repository
- lamm-mit/scienceclaw
- Last source activity
- March 14, 2026 at 06:18
- Detected SKILL.md language
- English
- Stars
- 250
- Forks
- 49
Install options
The review-first prompt is selected by default. You can switch to a direct command or download a local copy.
Review the source files
Read SKILL.md and any companion files shown by SkillsMP before deciding whether to install.
File Explorer
3 filesShowing SKILL.md
SKILL.md
Source instructions · Read-only preview- name
- conservation-map
- description
- Compute per-position conservation/entropy for an aligned peptide MSA (aligned sequences).
- metadata
- {"skill-author":"ScienceClaw demo"}
# Conservation Map
Compute conservation for each alignment column from an MSA.
Accepts either:
- `--aligned-json` (preferred): a JSON list of aligned sequences (safe even if sequences contain `-`)
- `--query`: JSON list or `;`-separated raw/aligned sequences (raw sequences will be aligned internally)
## CLI
```bash
python3 scripts/run.py --aligned-json '["AGC--K","AGCFFK"]'
python3 scripts/run.py --query "AGCKNFFWKTFTSC;FCFWKTCT"
```
View on GitHub